Aug 17, 2009 - 3:02 am
My husband was diagnosed -Mucinous adenocarcinoma of the Appendix in Nov. 07. His chemo is Oxaliplatin every 3 weeks and daily 4,000mgs. of Xeloda[14 on,7off]. He has completed his 5th round of Oxy. Recent CT showed no improvement. We will be going for consult on the 25th to discuss what we will try next. We already tried Avastin before starting Oxy. Husband was rushed to Emergency a couple of days later with very rare side effect! He woke up from a nap with symtoms of a stroke.He couldn't speak clearly and one side of his face was slightly droopy. I requested local hospital arrange for transfer to Stanford University Cancer Center [ where my husbands oncologist is]. The Avastin was causing the vessels in his brain to leak fluid, mimicking a stroke. Very rare, they had never seen this happen before. There were no lasting effects.
Explanation; Rare malignant growth characterized by progressive accumulation of mucus secreting tumor cells within abdomen and pelvis. Developes after a growth with the Appendix burst through wall of Appendix and spreads mucus producing tumor cells throughout the membrane that lines abdominal cavity[peritoneum]. As mucinous tumor cells accumulate, abdominal area becomes swollen and digestive function becomes impaired.
I do not know what next treatment will consist of. Their was mention of a possible clinical trial,will know on the 25th. I think we will take a holiday from chemo first.