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New Clinical Trial for Advanced Cancer -

lizzydavis's picture
Posts: 893
Joined: May 2009

Trial of New Drug to Blocks Cell Changes Available at NIH Clinical Center
Posted: 30 Jul 2009 04:00 AM PDT
Written by Kate Murphy.
An oral drug that blocks activity of enzymes that change proteins in cells that leads to cancer is being tested at the National Institutes of Health.
R935788 or Fostamatinib, a protein kinase inhibitor, is in a Phase II clinical trial for patients with several types of advanced cancer, including colorectal cancer.
Patients whose cancer has gotten worse on previous treatment are eligible to participate. The trial is being conducted at the NIH Clinical Center in Bethesda, Maryland.
Patients will take fostamatinib twice a day during 4 week cycles. They’ll see a doctor at the NIH Clinical Center at the beginning of each cycle. Weekly blood tests and blood pressure checks can be done in an outpatient clinic or by the patient’s own doctor.
There is no charge for medical care received at the National Institutes of Health (NIH) Clinical Center in Bethesda. Patients need to pay their own travel costs for the first screening visit, but once enrolled, the National Cancer Institute pays for transportation to the Washington area. During outpatient visits, NCI pays a small daily amount for for hotel and meals.
Patients are encouraged to maintain their own insurance to cover health care costs outside of the NIH Clinical Center.
To be considered for the trial, patients or their doctors should contact research nurses:
· Janelle Bingham, R.N.
· Phone: 301-435-2715
· jbingham@mail.nih.gov
· Mary Ann Yancey, R.N.
· Phone: 301-435-9227
· yancym@mail.nih.gov
Shivaani Kummar, MD is leading the study. She can be reached at 301-435-5402 or kummars@mail.nih.gov
Find more answers to your questions about the trial. A full description is on the NCI Clinical Trials PDQ.

lisa42's picture
Posts: 3661
Joined: Jul 2008

Thanks for this valuable information. I read about it myself this morning and so I'm bumping it to the top so others will also see it.

Take care,

snommintj's picture
Posts: 602
Joined: Mar 2009

I've been talking about this for weeks. I should start in two weeks, depending on what the surgeon tells me

lisa42's picture
Posts: 3661
Joined: Jul 2008


Yes, you have been talking about it! I read about it when you mentioned it awhile back and I wrote it down (fostamatanib, or something like that) and talked to my oncologist about the possibility of me doing it.
Since I still respond to irinotecan, I'm going to do that for now, but he said this other thing could be something we'd consider next if/when the irinotecan stopped working for me.
So thanks for getting it out there- we are hearing you!
By the way, hope you're feeling well now.

Take care,

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