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Peritoneal Cavity and Heated Chemo

MFS74's picture
Posts: 8
Joined: May 2009

Hello everyone......My name is Mark, I've posted a few times to this board and have been an avid reader since my dad underwent surgery on May 26th. His initial prognosis (based on normal CEA levels and PT/CT scans) was very good. However, when he went through surgery it turned out he was diagnosed with Stage IV colorectal cancer which had spread to the peritoneal cavity. As I'm through the initial shock and have had a chance to become educated, we have come up with an aggressive treatment plan for my dad. My dad has been treated at Mt. Sinai (in NYC) where the care has been very good. The team of doctors has suggested a second surgery which includes a partial stripping of the peritoneal cavity with heated chemo applied directly during the surgery. I understand the heated chemo has had pretty good results, but the surgery can be difficult. (They tell me its not Sugarbaker as they are using different chemo and only requires partial stripping). I was wondering if anyone had any experience with the surgical procedure/heated chemo and was willing to share those experiences with me. Thank you to everyone who has posted and responded on this board as it has been incredibly inspirational and helpful in coping with this difficult situation.

nudgie's picture
Posts: 1483
Joined: Sep 2006

I do not have any advice on the heated chemo, but have heard and read posts here about Sugarbaker method. I will pray for your Dad

MFS74's picture
Posts: 8
Joined: May 2009

Thank you for responding and thank you for your prayers.

Shayenne's picture
Posts: 2370
Joined: Jan 2009

....of this heating chemo, that all just sounds so new and promising, I'll have to find more on it. If I hear or see anymore additional issues with it, I will share it with you!


Fight for my love
Posts: 1530
Joined: Jun 2009

Hi Mark,you can google"what is heated chemo",then I got answer which may answer your question,the link is :http://www.sciencedaily.com/releases/2006/11/061103104037.htm,they have answer like:

The heated chemotherapy is designed to help reliably attack any residual cancer cells remaining after surgery. The consensus statement: "Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in the Management of Peritoneal Surface Malignancies of Colonic Origin", appears on the Web site for the Annals of Surgical Oncology.

HIPEC involves the use of conventional chemotherapy drugs heated to such a high temperature as to kill cancer cells. Additionally, by bathing the abdomen with heated chemotherapy immediately following surgery, a higher dose of medication can be used than would normally be tolerated by a patient if given intravenously -- the traditional way chemotherapy is administered. Before releasing today's consensus statement, the PSMG reviewed several peer-reviewed clinical articles published by nationally renowned oncology researchers and surgeons to establish standardized methods to deliver HIPEC; define patient selection criteria; and improve surgical techniques.

In 2005, an estimated 145,000 new cases of colorectal cancer were diagnosed in the United States, according to the American Cancer Society. Doctors estimate 30 percent of these patients would benefit from surgery with HIPEC. The published data on the treatment of patients with Stage IV colorectal cancer, with combinations of tumor removal surgery and chemotherapy, showed a median survival of greater than 20 months, compared to six-month survival with traditional intravenous chemotherapy alone.

"HIPEC is an aggressive surgical treatment for end-stage cancer patients, with promising results," says Jesus Esquivel, M.D., lead author of the consensus statement and director of the peritoneal surface malignancy program at St. Agnes Healthcare in Baltimore. "This innovative therapy, with surgery, is helping to significantly improve, and extend the lives of patients who are in desperate need."

Patients whose colon cancer recurs, and those with cancer that has spread to other parts of the body, involving the abdomen or peritoneal cavity, are the patients who benefited most from the combination of surgery followed by HIPEC. Although not addressed in the consensus statement, surgical oncologists are utilizing the treatment for patients with other forms of abdominal cancers, including pancreatic, ovarian, and gastric cancer.

The PSMG is currently 72 national and international surgical oncologists from 55 cancer centers in 14 countries, who are dedicated to education, research, and improved care for patients with advanced abdominal cancers.

Hope you can find more information by google it,I also send my best wishes and best thoughts to you and your father.

Posts: 11
Joined: Jun 2009

I am also interested in this procedure as my Mom was diagnosed with cancer during a surgery in March of this year. This surgery has been recommended to her and she is terrified of it. From what I've heard it has had some good results so I am hoping if we are still told it is a good choice after this initial round of chemo that it will be an answer to our prayers and that my mom will accept it. Any information anyone can give on this surgery is much appreciated. This is the hardest thing I have ever had to deal with in my entire life. MFS74 I hope things are going well with your Dad.

christellabelle's picture
Posts: 25
Joined: Jun 2009

Hi Mark,
I had a recurence of colon cancer in my pelvic area, i went to surgery for a complete hysterectomy, and i had a chemo wash, and it was at mount sinai hospital as well. As the info mentioned it above, it's just a chemo heated at a certain degree to target any left over cancer cell circulating the cavity or organ. They do it right after removing the tumor and before closing the cavity. for some they leave a tube in order to receive more wash, but others like me i only got one wash. The type i had did gave me some nausea which the doctor had already told me. That's prety much it for me, it did not interfere with my healing from the surgery or nothing so, i don't think you need to worry too much as far as the wash. I know it's fifferent for each person, so ask your doctor how many chemo wash he gonna have? if he going to require a catheter? and what are the side effect?
good luck

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