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A question

Fight for my love
Posts: 1530
Joined: Jun 2009

Hello everybody,I have a question here:5-FU,Oxaliplatin,Capecitabine and Xeloda,and so on,all of them are standard and regular medications for chemo treatment for colon cancer,and they are all "antimetabolite",so what's the difference between them? Thanks a lot.

ADKer's picture
Posts: 150
Joined: Aug 2008

I am not really qualified to answerr your question, but here is a web site that might be helpful: http://www.nlm.nih.gov/medlineplus/druginformation.html If you google a drug, the manufacturer's site for the drug should come up, which might also provide more specific info about how the drug works.

Fight for my love
Posts: 1530
Joined: Jun 2009

Thank you very much,ADker,the website you provided is great!Thanks a lot.

PhillieG's picture
Posts: 4912
Joined: May 2005

Is this Riddle Friday a day early?

Did you google it?

Here is one explanation

"An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism. Such substances are often similar in structure to the metabolite that they interfere with, such as the antifolates that interfere with the use of folic acid. The presence of antimetabolites can have toxic effects on cells, such as halting cell growth and cell division, so these compounds are used as chemotherapy for cancer."

source - Wikipedia

kimby's picture
Posts: 804
Joined: Oct 2007

Well, they are for the same purpose but have different properties and metabolize differently in the body. Some work for one type of crc, some for another. Some for some people but not others. Some metabolize in the liver at a higher rate. Like Tylenol and Advil...same purpose, different outcomes. I think that's right but I didn't go to medical school. Wow, what a scary thought. You really don't want me to be your doctor!


Fight for my love
Posts: 1530
Joined: Jun 2009

Thanks a lot for all of your answers!

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