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features of moderately differentiated squamous cell carcinoma

Posts: 1
Joined: Jun 2009

Hi All,

I have a problem in my thorat for which doctor said there is some muscle growth and refer to do biopsy. The biopsy result was "moderately differentiated squamous cell carcinoma". Could anybody suggest what it is and what to do next??

ljoy's picture
Posts: 94
Joined: Dec 2007

I copied this off a website for cancer. I would think you need to be referred to a Medical Oncologists for further evaluation and treatment.

Squamous cell carcinomas are graded according to their degree of differentiation and designated as well, moderately, or poorly differentiated. Well differentiated tumors are recognized as exhibiting orderly stratification, obvious cellular bridges, and keratin pearl formation. In contrast, poorly differentiated squamous cell carcinomas are noted for their lack of keratinization and lack of intercellular bridges. Moderately differentiated tumors fall somewhere in between. Tumors are graded with respect to their least differentiated areas. The criteria for assigning grade are not precise and there are overlaps between the three categories.

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