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psa .14 then .04 after surgery

Posts: 24
Joined: Feb 2004

I had radical prostatectomy on 7/25/03, gleason 7 and a little cancer got into the capsule and on the edges of the inked margin. My first 3 month follow up psa was 0.14 and then the second 3 month follow up was 0.04(just this week). The direction is great and I am happy the psa went down but I am curious why it was at 0.14 the first time. My doctor says that it doesn't usually happen that way (and he was concerned when he saw the original psa) but sometimes it does. I am curious if anyone had a similar situation and did the psa ever go back up again? Thanks and God bless. Mike

Posts: 140
Joined: Sep 2001

I assume from your doctors statement he believes to have contained ALL of the cancer? If there is doubt, have you discussed radiation as a followup?

As to the psa; my doctors weren't alarmed with a little jumping around -- they do not want to see an upward trend. Check with your doctor but believe he is looking for something leveling off and dropping to near zero?

I would definetly check re: radiation if there is any chance that some of the cells did not get removed!

God Bless and stay in touch.

Posts: 24
Joined: Feb 2004

I still have not seen anyone go from a higher psa (0.14) to a lower psa 0.04 after radical prostatectomy. The psa is usually already at the lowest. Has anyone else experienced their psa going from higher to lower? Just curious. God bless. Mike

Posts: 7
Joined: Aug 2000

The PSA is sometimes not accurate. I would not worry about why but worry about it staying down at that level. Hopefully it will continue to drop - keep close watch on it.

nodawgs's picture
Posts: 117
Joined: Mar 2001

Maybe I missed something, but I don't understand why your doc was surprised. Some minor, but localized, post-operative infection activity could have caused a non-prostate cancer related elevation in prostate-specific antigens (PSA). Usually, they simply prescribe an antibiotic and re-test in 30 days or so.

Posts: 24
Joined: Feb 2004

Hi nodawgs!!! He looked at that possibility also but I had no fever or any signs of infection and this initial psa was taken 3 months after surgery. If there were any post op infection there probably would have been other signs earlier than the 3 month time period. But thanks for your heads up - it was something he considered. Thanks and God bless. Mike

Posts: 8
Joined: Apr 2004

Hello Mikeburr, I had a prostatectomy on 4/15/04 and I just had my 2nd PSA test. My first one ( 3 months after the RP ) had a reading of .2 Doctor said to not worry because my system was probably still filtering the PSA out , my 2nd test last week came back a .0 , no trace of anything. I also had capsule break through. Read my post from last May on this forum.

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