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Chemo treatment

Posts: 1
Joined: Jan 2004

I am a 51 year female. I had surgery for colon cancer on 12/31/03. My cancer is in Stage III; there were 2 lymp nodes that were cancerous, and possible blood vessels involvement; because of the size of the tumor. I will be starting my chemo treatments within the next two weeks. The two treatment plans offered by two different doctors are 5-FU taken alone weekly for a six period and oxaliplatin taken with 5-FU given every other week with a total of 12 treatments. I would like to know if there in anyone who has had experience with the new treatment oxaliplatin. What were some of the side effects experienced with oxaliplatin. I understand that 5-FU has been the standard treatment for colorectal cancer for years and this new drug, oxaliplatin, was approved by the FDA in August of 2002.

I am looking to talk with someone who has had experience taking the new drug, oxaliplatin.

cmcl's picture
Posts: 79
Joined: Jan 2004

I was diagnosed with Satge IV in 6/03. I'm 39. I'm just finishing my round of chemo, last treatment is next week. I take Oxali/5FU/Leucovorin, the 5FU is infused for 48 hrs through a pump, it's like a fanny pack. My biggest side effect was nausea, sometimes vomiting. There are many anti nausea meds offered. With Oxali you cannot be exposed to any cold temperatures. You'll learn to drink room temperature beverages and bundle up when you go outside, always wear gloves and a scarf to cover your nose and mouth. My hands and feet were effected the most. I didn't have too much trouble with diarreah, but I found taking Meatamucil helped keep me normal. I also take calcium/magneseum before and after each treatment, it's supposed to help with the side effects from the cold. I'm not sure it works, but it can't hurt to have a little extra cal/mag.
The number 1 thing is to keep positive! You will get through this. A support person to go with you to the doc/treatments is very helpful. It helps to have someone write down info while you're talking to the doc and it's comforting just to have another person with you
I hope this has been helpful. Let me know if you have any other questions, I would be glad to help.

Posts: 20
Joined: Jul 2003

Hi! I had all the side effects from oxaliplatin that my onc told me I would have. The reaction to cold was quite awful, but it would subside several days after receiving it. I'm 6 months out of treatment now, and my hands and feet are still numb and tingly. My onc said this may be permanent. I don't like it, but I think it's worth it.

I wish you the best with your treatment.

Posts: 176
Joined: Mar 2003

Welcome to the semi colons
I had my surgery june 2002, did chemo and then rads with 5FU am now on oxi with 5FU/Lev have had 2 treatments so far. I am experienceing tiredness and a weakness in my legs some minor nausea after treatment so far. I have had the tingleing in hands and feet when I wasn't careful. Again welcome and keep us informed of your progress.

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