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325 Mg of Asprin

Nana b's picture
Nana b
Posts: 3045
Joined: May 2009

I was lectured by the nurse preparing me for my colonsocpy yesterday. She said that I should not be taking 325 mg a day of asprin, so I have a call in to my oncologist to see if it's a no, no. FYI for those taking 325 mg of asprin, you may want to ask also. She stated asprin at that strength is not good, especially those with liver problems and or/desease.

She lost her husband to colon cancer a couple years back.

KATE58's picture
KATE58
Posts: 300
Joined: Nov 2009

THE DAILY DOSE IS 81 MG
WHICH IS 1 BABY ASPERIN

karguy's picture
karguy
Posts: 1024
Joined: Apr 2009

I took 3 tablets of asprin,and still do,the only time I couldn't take any was during chemo,and radiation,otherwise the dr. said it was no problem.I have taken it daily for years.I guess it's up to the drs.,good luck.

geotina's picture
geotina
Posts: 2118
Joined: Oct 2009

I take one baby aspirin per day. My doctor's recommendation. At first she said I should be taking an aspirin a day and later in the visit clarified that it is one baby aspirin per day. There is a history of heart problems in my family and that is the reason she recommends a baby aspirin per day. George does not take any aspirin. Tina

Kerry S's picture
Kerry S
Posts: 607
Joined: Dec 2009

I take one 325mg a day and have for many years. It keeps my arthritis in check. I only had to stop before surgeries and the colonoscopies. The doc told me that was fine.

I read an article that said thoes of us that take asprin have better outcome with colon cancer. However I would listen to your doc. I am wired different then most people.

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

Studies show that it takes the 325 mg strength to make a difference in prevention of cc. Up to 30% reduction in recurrence risk for Stage III.

Heading to dinner with gal pals so don't have time to find the paper/ link. TTYL

jscho
Posts: 62
Joined: Jun 2009

I find the issue of dosage not clear. I have two articles written by the same researchers that
seem to say contradictory things. In the Chan and Fuchs article of 2008 (Gastroenterology 2008, 134 pages 21-28) the authors say:
"The apparent benefit associated with aspirin use was substantially greater with increasing dose...men who used the equivalent of 0.5-1.5 standard aspirin (325 mg) per week did not have significantly lower risk of colorectal cancer (multivariate relative risk (RR), 0.94, 95% CI 0.75-1.18)..."
They go on to say that the 6-14 aspirin per week had a multivariate RR of 0.72, and >14 aspirin had a RR of 0.3 (based on 4 cases).

However, in the recent JAMA article by Chan and Fuchs (JAMA, 302 pages 649-659) they claim:
"the association between postdiagnosis aspirin use and survival was modestly dose-responsive". In this table, the adjusted HR (hazard ratio) is 0.57 for 0.5-5 aspirin per week, and 0.46 for >= 6 aspirin (actually the same within the statistical uncertainties). They do claim the COX2 status is important, and differentiate on this basis.

Based on this information, it seems that there is a clear benefit to taking aspirin, but the dosage level is not established. I suppose it is safest to take around 1000 mg a week to avoid complications but receive some benefit.

Sundanceh's picture
Sundanceh
Posts: 4408
Joined: Jun 2009

My new onc at the new hospital told me after lung surgery to start right away on 325mg a day aspirin and NOT 81mg aspirin - I asked him 3 different times and got the same answer each time.

Apparently 325mgs make the difference in colon cancer recurrence and to slow down the growth of polyps.

I see him in another week, so I'll ask again - have not started yet, but will if he recommends it.

-Craig

coloCan
Posts: 1956
Joined: Oct 2009

Supposedly it is most effective for those whose tumor's are/were known as "COX-2 overexpression." In any event, always check with your oncologist first......Steve

fringetree
Posts: 66
Joined: Dec 2009

To those of you taking aspirin, does it upset your stomach at all?

KATE58's picture
KATE58
Posts: 300
Joined: Nov 2009

I am not allowed to take asperin or any other nsaid, because of platelet problems.
I know the daily dose for those with a history of HEART problems is 81mg (1 baby asperin)
I did not know it was different for colon cancer
I stand corrected.:-)
Learning all the time!

fringetree,
if you take it with food it should not upset your stomach.
Kate

Nana b's picture
Nana b
Posts: 3045
Joined: May 2009

When I went to my 325 mg of ASPRIN, B12 DROPS, CALCIUM, VITAMIN D3, VITAMIN C AND FISH OIL, MY ACID REFLEX WENT COMPLETELY AWAY. I HAVE HAD ACID REFLEX FOR ABOUT 5-7 YEARS. NOT SURE WHICH MADE IT GO AWAY BUT ONE DID.

EXCUSE THE CAPS.......ON MY WAY OUT THE DOOR, HUBBY IS SICK, NEED TO GET SOME MEDS.

Kathryn_in_MN's picture
Kathryn_in_MN
Posts: 1258
Joined: Sep 2009

No aspirin - on Coumadin. Bleeding risk.

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Nana b's picture
Nana b
Posts: 3045
Joined: May 2009

I'm not on chemo, or I would not take any of these supplements. You know my ONC has not called me. I need to follow-up.

KATE58's picture
KATE58
Posts: 300
Joined: Nov 2009

When I was on avastin my doctor said
no aspirin,vitamin E,or fish oil capsules.

They also told me that before any surgery ,stent removal/placement
( for 2 yrs,I had to get a stent replacement in my kidney every 3 months)
but I do have a platelet problem,they like to stay below 100,000

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KATE58's picture
KATE58
Posts: 300
Joined: Nov 2009

One day at a time!
remember,tomorrow is just a future yesterday !

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