small cell - chemo is not working!

kaitek said:

Hello nancyrn,

I have to preface that my suggestions of medical treatments relate more to non-small cell lung cancer, but maybe you can look further into them after hearing about them here. Some may be considered still experimental.

Talk to your dad's oncologist about targeted drug therapies that work on the metabolic functions of the cancer cells such as the growth of new blood vessels, which cancer cells are dependent on. I know for NSC, Avastin has been approved by the FDA. Avastin works on shutting down the formation of new blood vessels.

Tarceva is another targeted drug treatment that works on another of cancer cells' growing patterns. It is most effective on people with the EGFR mutation. This mutation can be tested on a cancer sample. Insurance should cover the cost as it is part of the diagnostic tests.

With that said, I was assured by my mom's thoracic surgeon that even people not having that EGFR mutation can fully recover [with Tarceva]. At this point when conventional chemo may not be effective, you have to expand your trials, right?

Though those targeted drugs have side effects, many people tolerate them much better than chemo. But Avastin does have a considerable fatal effect for a few people of lung hemorrhage and serious effects of stomach perforation and high blood pressure (which that is controlled with counter drugs).

I have heard about thermal radiation that uses either heat or freezing temperatures to kill the cancer cells. There's also photodynamic treatment where the patient is injected with a photo-sensitive chemical and then, lasers are applied to "blind" the cancer cells to death. I've yet to actually read anyone receiving that type of treatment.

A better source of these innovative options can be read from the National Cancer Institute site. You should check that site out for possible treatments for your father. It seems time is of the essence for him, too.

Beyond the conventional treatments, I have come across interesting studies on maitake mushrooms. Keep in mind, I discount any article that tries to sell anything or is posted on a site promoting a commercial product. It's too biased and it reads too much as from a snake oil salesman.

In the articles extolling maitake mushrooms (specifically in the form of D-fraction), studies have been cited where tumor regression was obtained in the range of 90% to 95%. In addition, this extract minimizes the side effects from chemo and radiation, even the low white blood cells count.

I am intrigued by the D-fraction and have it as a possibility. If my situation was dire, I might resort to it. I looked into the purchase on various sites and it wasn't too bad. It is more expensive than regular vitamins (but not too much as COQ-10).

I've put my mom on a dietary regiment that includes a raw, minced garlic clove; cruciferous veggies (with emphasis on broccoli, radish and daikon); raspberry jam (for its ellagic acid that has apoptosis properties); soy milk or tofu (for the genistein, which prevents angiogenesis - formation of new blood vessels); chili peppers (for apoptosis) and tomatoes. A cup of V8 juice has a lot of the vegetables with anti-cancer benefits. It may be easier to consume that regularly. She also takes vitamin D3+calcium and selenium supplements (I eliminated the multivitamin because of my concern of the antioxidant effects and I wanted her nutrients to be more from foods instead).

To be sure, I can't guarantee you that any of those supplements are effective but my mother has been responding well in her therapy. Is it the chemo of Taxol and Carboplatin and/or the supplements? I can't tell you, but I wouldn't depart from either.

I would urge you to research further on your own and discuss everything with your dad's oncologist. It certainly doesn't hurt to modify his foods though.

Much luck and good prospects for your dad. If you have any questions, you're always welcomed to ask here or by private message.