Treating rectal tumor with Cipro antibiotic!

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Lightfootgar
Lightfootgar Member Posts: 3
in Colorectal Cancer #1

Don't know if anyone else has an experience with this. Prior to being diagnosed recently with my rectal tumor via colonoscopy there was a couple of surgeons and a physician who with a couple of CT scans  decided I had a rectal abscess. They gave me Cipro for 2 weeks to try to see if it would have an effect, and it did. During that two weeks what they saw in the CT scan which they believed to be a rectal abscess was actually my tumor and it had reduced in size over that period of time by almost a third. He told me just to continue on Cipro. A couple of weeks later I had my colonoscopy which revealed the actual problem. I brought that up with the chemotherapy oncologist and he's not sure about the findings and how they apply. I went online and found a couple of clinical studies involving antibiotics for rectal cancer. Is there actually other help for us out there and because Cipro is so much cheaper and more accessible that the cancer industry might be hiding some of these findings? 

I'm only 5 weeks into my radio chemotherapy and as soon as I get my next CT scan I'm thinking of taking a couple of weeks off to try Cipro or mix it in with what I'm doing I don't know. Does anyone have any information about this or perhaps have tried or know someone that has tried it?  

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  • Tueffel
    Tueffel Member Posts: 327 Member
    #2
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    New info

    Because of you I googled ciprofloxacin with colon cancer (quite similar cancers). There are studies that show that this antibiotic has an apoptotic effect on cancer cells in cultured cells. Apoptosis is the programmed cell death, a feature misding in cancer cells. These studies I found were all from 2020, so probably new and not put into the guidelines yet for treatment. Maybe even they are no clinical trials yet that would approve cipro in use of colorectal cancer. So yeah what happened to your xancer is more or less an incidental finding that applies to studies but no clinical trials are done yet for this (they should). 

    I will put that definetely on my list to ask my dads oncologist the next time I talk to him. So thank you!

    Tueffel

  • worriedson714
    worriedson714 Member Posts: 333 Member
    #3
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    study

    There is actually a study at ncbi.nlm.nih.gov/pmc/articles/PMC7378927/ about this which says well they can help . They can also induce cancer generation by disrupting intestinal microbiota which further promotes chronic inflamation alters normal tissue metabolism , leads to genotoxcity and weakens the immune system to bacterial malnurtrition . So well I am happy they seem to have done you good I would be careful of long term use . This is why I suspect your oncologist is unsure about how this applies .

  • Real Tar Heel
    Real Tar Heel Member Posts: 307 Member
    #4
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    worriedson714 said:

    study

    There is actually a study at ncbi.nlm.nih.gov/pmc/articles/PMC7378927/ about this which says well they can help . They can also induce cancer generation by disrupting intestinal microbiota which further promotes chronic inflamation alters normal tissue metabolism , leads to genotoxcity and weakens the immune system to bacterial malnurtrition . So well I am happy they seem to have done you good I would be careful of long term use . This is why I suspect your oncologist is unsure about how this applies .

    I had a tooth abscess and was

    I had a tooth abscess and was on an antibiotic while on chemo. Concerned about the effect on the gut microbiome I took a probiotic along with it. I don't know whether it helped the effectiveness of chemo but it definitely helped with diarrhea. My CEA has been cut in half since I started chemo this round so maybe looking okay for now.

  • SnapDragon2
    SnapDragon2 Member Posts: 717 Member
    #5
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    Yes, I did come across that

    Yes, I did come across that researching.  Forgot about it, thanks for the refresher.  Also, celindamyocin is reported to kill CSC.

  • Lightfootgar
    Lightfootgar Member Posts: 3
    edited June 2021 #6
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    Tueffel said:

    New info

    Because of you I googled ciprofloxacin with colon cancer (quite similar cancers). There are studies that show that this antibiotic has an apoptotic effect on cancer cells in cultured cells. Apoptosis is the programmed cell death, a feature misding in cancer cells. These studies I found were all from 2020, so probably new and not put into the guidelines yet for treatment. Maybe even they are no clinical trials yet that would approve cipro in use of colorectal cancer. So yeah what happened to your xancer is more or less an incidental finding that applies to studies but no clinical trials are done yet for this (they should). 

    I will put that definetely on my list to ask my dads oncologist the next time I talk to him. So thank you!

    Tueffel

    My pleasure. Anything that I

    My pleasure. Anything that I have to contribute to this great source of information I will gladly share. I'm glad I found this website, kind of helps with the anxiety of feeling like you're alone.

  • Lightfootgar
    Lightfootgar Member Posts: 3
    edited June 2021 #7
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    worriedson714 said:

    study

    There is actually a study at ncbi.nlm.nih.gov/pmc/articles/PMC7378927/ about this which says well they can help . They can also induce cancer generation by disrupting intestinal microbiota which further promotes chronic inflamation alters normal tissue metabolism , leads to genotoxcity and weakens the immune system to bacterial malnurtrition . So well I am happy they seem to have done you good I would be careful of long term use . This is why I suspect your oncologist is unsure about how this applies .

    ?

    ?

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