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Interesting Clinical Trial Immune Cell Stimulation

SantaZia
Posts: 64
Joined: Apr 2018

I did a final consult with a Radiation Oncologist at UNM Cancer today. He thought I would be a good candidate for this.  It looks interesting but would be with traditional Photon versus Proton. I am leaning towards Proton, but as a promising 3rd phase trial I thought I would share with everyone. See my Proton post for my details if needed. 

ProstAtak®Trial- Newly Diagnosed Intermediate and High Prostate Cancer http://www.advantagene.com/

Prevention of prostate cancer recurrence in intermediate and high risk patients is the goal of Advantagene’s Phase 3 study.  Results to date from our early clinical studies in prostate cancer, including newly diagnosed prostate cancer, have been extremely promising. We are currently conducting a randomized, fully blinded, placebo controlled Phase 3 clinical study examining GMCI (ProstAtak®) in combination with standard radiation therapy in patients with newly diagnosed, intermediate to high risk localized prostate cancer. This 711 patient study is being conducted under a Special Protocol Assessment (SPA) agreement with the FDA. 

Study Co-chairs: 

Peter Scardino, MD, 

Chairman of the Department of Surgery 

Memorial Sloan Kettering Cancer Center 

Theodore DeWeese, MD 

Chairman, Department of Radiation Oncology and Molecular Radiation Sciences 

Johns Hopkins Medical Institute      

 

 

 

 

 

 

 

 

To download a copy of patient brochure, Click ProstAtak™ patient brochure

Clevelandguy
Posts: 456
Joined: Jun 2015

Hi SantaZia,

I know if I ever need radiation it will be with Proton not Photon.  The following quote is from a web site that specializes in Proton treaments.

"Proton therapy is precise. Unlike traditional (photon) radiation, protons travel directly to the site of the tumor and stop. They deliver radiation to the tumor but do not continue through the body. As a result, healthy tissues near the tumor do not receive doses of radiation that they don’t need. This benefit is particularly important for tumors located in or near vital organs" .

No exit damage sounds good to me...........................

Dave 3+4

Old Salt
Posts: 720
Joined: Aug 2014

The (often used) statement that protons will just hit the cancer can't be true. Even if all protons were to stop at the cancerous site, they still have to travel through tissue to get there.

See https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080851/

for a more serious discussion of this topic.

SantaZia
Posts: 64
Joined: Apr 2018

Thanks Old Salt!

 

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