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Dietary patterns and prostate cancer risk study

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Nutrient-based dietary patterns and prostate cancer risk: A case-control study from Italy - Abstract

Published on 11 March 2014


PURPOSE: The role of various foods and nutrients, and their combinations, on prostate cancer risk remains largely undefined.

We addressed therefore the issue of complex dietary patterns.

METHODS: We analyzed data from an Italian case-control study, including 1,294 men with prostate cancer and 1,451 hospital controls. We carried out an exploratory principal component factor analysis on 28 selected nutrients in order to identify dietary patterns. We estimated odds ratios (ORs) and corresponding confidence intervals (CIs) using logistic regression models on quintiles of factor scores, adjusting for major confounding variables.

RESULTS: We identified five dietary patterns, labeled "Animal Products," "Vitamins and Fiber," "Starch-rich," "Vegetable Unsaturated Fatty Acids (VUFA)," and "Animal Unsaturated Fatty Acids (AUFA)." We found positive associations between prostate cancer and "Animal Products" (OR for the highest vs. the lowest score quintile: 1.51, 95 % CI 1.16-1.96), "Starch-rich" (OR 1.50, 95 % CI 1.16 1.93), and "AUFA" (OR 1.32, 95 % CI 1.02-1.70) patterns. No significant associations emerged with "Vitamins and Fiber" (OR 0.93) and "VUFA" (OR 1.16) patterns.

CONCLUSIONS: Our findings suggest that a diet rich in animal products, including several types of meat and dairy products, as well as of (refined) cereals and sugars has an unfavorable role on prostate cancer.

Written by: 
Rosato V, Edefonti V, Bravi F, Bosetti C, Bertuccio P, Talamini R, Dal Maso L, Montella M, Ferraroni M, La Vecchia C, Decarli A.   Are you the author? 
Department of Epidemiology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Via Giuseppe La Masa 19, 20156, Milan, Italy.

Reference: Cancer Causes Control. 2014 Apr;25(4):525-32. 
doi: 10.1007/s10552-014-0356-8

PubMed Abstract
PMID: 24515125

UroToday.com Prostate Cancer Section



Posts: 261
Joined: Sep 2010

People under 65 who eat a lot of meat, eggs and dairy are four times as likely to die of cancer or diabetes, study suggests:


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