Research item on how variations in KRAS-wild status impact Cetuximab effectiveness

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coloCan
coloCan CSN Member Posts: 1,944 Member
in Colorectal Cancer #1

www.biomedcentral.com/1471-2407/13/169/abstract

(there's more info in the link attached but this is all rather "technical")

Comments

  • steved
    steved CSN Member Posts: 834 Member
    #2
    Interesting

    Increasing thespecificity of chemo would be great. Preventing people who won't benefit from a drug having to be exposed to it will reduce the harm associated with them. 

    Steve

  • coloCan
    coloCan CSN Member Posts: 1,944 Member
    #3
    steved said:

    Interesting

    Increasing thespecificity of chemo would be great. Preventing people who won't benefit from a drug having to be exposed to it will reduce the harm associated with them. 

    Steve

    From one steve to another: there's a little more of such info

    here

    www.onclive.com/publications/obtn/2013/march-2013/molecular-pathways-pathways-and-more-pathways/1 

    Tho EGFR and KRAS get the most attention. (Hope with each passing day you feel better)

     

  • steved
    steved CSN Member Posts: 834 Member
    #4
    coloCan said:

    From one steve to another: there's a little more of such info

    here

    www.onclive.com/publications/obtn/2013/march-2013/molecular-pathways-pathways-and-more-pathways/1 

    Tho EGFR and KRAS get the most attention. (Hope with each passing day you feel better)

     

    Is practice keeping up?

    Meeting with oncologist next week and will ask if testing anything more than kras in practice yet.

    Slowly recovery moving forward here, thanks for your continued academic stimulation,

    Steve

  • coloCan
    coloCan CSN Member Posts: 1,944 Member
    #5
    steved said:

    Is practice keeping up?

    Meeting with oncologist next week and will ask if testing anything more than kras in practice yet.

    Slowly recovery moving forward here, thanks for your continued academic stimulation,

    Steve

    perhaps you'll find this interesting

    http://cancerres.aacrjournals.org/content/73/7/2059

    Seems like every research team has their "pet" biomarker or factor that may predict future,so to speak. All here are aware of CEA but there may be other indicators as well that may be more pertinent

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