rough scan results

Sounds like a tough day Jeff
Just remember amongst that news the tumors in the colon are stable... I have heard that the 5FU is really effective and just think 24/7 for 8 weeks sounds like the lung tumors will have no chance!!!!

Jeff
I'm so sorry to hear this...you're a tough guy to keep swallowing that stuff non-stop...I tip my hat to you.

It sounds to me like the onc wants to try this to see if you can tolerate this treatment, since it appears that you are having issues with the other combinations.

I did 5fu by itself for six straight weeks, 24/7...but it was in combination with radiation.

I hope for the best here...and hopefully the new growths will at least stabilize for the interim with this treatment. You've done alot of the things there are to do.

Have you been KRAS tested? If you're 'wild' you would be a candidate for Erbitux or Vecitibix, which many people are having success with. If you're 'mutant' that means that you would not be eligible for this, as this treatment would not have the response you would be looking for and the toxicity involved would negate any benefit, if at all.

But, it's worth knowing...cause wild opens up another door for you.

I know you're worried, who wouldn't be? I worried that if Folfir failed me at some point, then I'm down to the other two you mentioned, and maybe that new one being touted.

It's worrisome alright...but we're pulling for you. That pump can really be a drag carrying it all the time for so long...mostly you can ignore it, but other times it lets you know it's there.

Keep trying, Jeff!

-Craig

5FU pump
I did the pump back in 2004 before we had xeloda and really it is no different than taking xeloda each day apart from the inconvenience of wearing the pump. I am not sure why you simply don't use xeloda though which is basically the same drug as a tablet (though accept may be issues of cost and access).

I tend to tolerate it fairly well and don't remember major problems from being on the pump for 5 weeks. It is individual but is certainly for me a well tolerated drug compared to oxaliplatin,

Hope things go well for you,
steve

dmj101 said:

one day at a time..
WOW.. I
one day at a time..
WOW.. I hope and pray for the best for you.. i know you must be so dissapointed..
keep on fighting babe.
It isn't easy but you will get there-- there was some positives in that report so hang on to them and find some peach there..
take care and keep us posted..

Jeff, you didn't mention
Jeff, you didn't mention Irinotecan either. Have you been on that before?
How was the 24-hour urine test? OK?
I know it's concerning, but maybe the 5FU 24/7 won't be so bad, I assume it will be at a reduced strength, but for a longer period of time.
Wonder if you could stay on the Avastin, but get some different pre-meds to help. Were you mostly fatigued?
I will pray for you every day, as I am doing for everyone here.

steveandnat said:

thanks
Its great hearing from you all. I tried erbitux but was Iras mutant so had to stop. My urine was high protein so giving a break from that. Seeing a urologist Friday not looking forward because of the test they have to do. The scan sheer a cyst and they want to have a closer look. Thanks again. Jeff

Take a deep breath...

Jeff,

You have been thru so much. There are so many setbacks in this journey. Know you have a lot of support, prayers, and hope here...we're rooting for you.

Cathleen Mary

smokeyjoe said:

Like Steve I'm wondering why
Like Steve I'm wondering why not the pills?? My onc. didn't offer them, I asked for them...he said they're less effective than the folfiri though, so he didn't understand why I wanted to give this a try. Best of luck to you, I feel for you...I hate that friggen pump.

Did you asked about Regoranfenib ?
Praying for you , have a big hug!