Anyone familiar with Taxol?

herdizziness
herdizziness Member Posts: 3,624 Member
My sister-in-laws cancer has spread more (originally breast cancer 15 years or so ago, then came back in bones and lungs last year, she was on hormone treatment for it, but it did not work) she ended up in hospital with one lung having a liter of fluid they took out, and goes tomorrow to get the other lung's fluid removed. They announced that the hormone therapy wasn't working and that with Taxol she had a 80 percent chance at great shrinkage of the tumors. They are going to give her a port next week and then the next Monday start with Taxol. So if anyone can give me heads up to how they did on Taxol, it would be much appreciated.
Thank you so much,
Winter Marie

Comments

  • geotina
    geotina Member Posts: 2,111 Member
    Hi Marie:
    Run this by the breast board. They are very active and may have more answers for you.

    If this is the red/orange color chemo then the ladies in George's chemo lab get very nauseaous on it so make sure she has good meds for home.

    Take care - Tina
  • herdizziness
    herdizziness Member Posts: 3,624 Member
    geotina said:

    Hi Marie:
    Run this by the breast board. They are very active and may have more answers for you.

    If this is the red/orange color chemo then the ladies in George's chemo lab get very nauseaous on it so make sure she has good meds for home.

    Take care - Tina

    Tina
    Thank you!
  • annalexandria
    annalexandria Member Posts: 2,571 Member
    I did carbo-taxol..
    so my experience may be a bit different because of the combination of drugs. But overall, it was an easier treatment than the FOLFOX I did first. Worst part of it was losing my hair (and that is a side effect of both drugs, so pretty much a given). Getting prepared ahead of time with a wig and some cute scarves (she should check out the beaubeau website..really stylish pre-tied scarves that I still wear even tho I now have hair). The neuropathy can get bad-where I was treated all patients on this regimen were told to take glutamine powder daily to help with this. And aches and pains can develop, as taxol in particular damages joint/muscle cells. That was my most problematic physical symptom. I took ibuprofen and hydrocodone, which helped. The nausea for me was mild, taking the occasional Ativan was sufficient. Hope this helps! I'll be thinking of your SIL, hoping for the very best. Ann
  • ktamp
    ktamp Member Posts: 81

    I did carbo-taxol..
    so my experience may be a bit different because of the combination of drugs. But overall, it was an easier treatment than the FOLFOX I did first. Worst part of it was losing my hair (and that is a side effect of both drugs, so pretty much a given). Getting prepared ahead of time with a wig and some cute scarves (she should check out the beaubeau website..really stylish pre-tied scarves that I still wear even tho I now have hair). The neuropathy can get bad-where I was treated all patients on this regimen were told to take glutamine powder daily to help with this. And aches and pains can develop, as taxol in particular damages joint/muscle cells. That was my most problematic physical symptom. I took ibuprofen and hydrocodone, which helped. The nausea for me was mild, taking the occasional Ativan was sufficient. Hope this helps! I'll be thinking of your SIL, hoping for the very best. Ann

    I'm on carbo and taxol for
    I'm on carbo and taxol for ovarian cancer. I get the carbo every 3 weeks and taxol every week. The carbo seems to be the bigger evil of the two drugs. I have two bad days after my chemo. I get chemo on wednesday and friday and saturday are my bad days. Mainly I am fatigued on the taxol. I've had no nausea with it. I'm starting to get neuropathy in my hands and feet after my 5th treatment. I take vit b 6 100mg three times a day which does help with the neuropathy. This was recommended by my oncologist although there is no research that I know that supports it. They have found that it helps and it seems to be helping me. It seems to be worse when I miss a dose. My hair bit the dust after 3 weeks. I've got a wig but I'm more self conscious with it. I'm always afraid it is going to move around and be on crooked. So I just wear turbins and scarves. It's more comfortable and I'm over being self conscious about not having hair. It is what it is. I've got all sorts of scarves and caps. Taxol is very hard on the bone marrow when given weekly. I've missed one treatment for low wbc counts and they had to lower my dose with my last treatment. I get neupogen shots 3 days a week to help boost my count. The neupogen is by far worse than the taxol IMO. It gives me lots of bone aches. Otherwise I've had very little aches with the taxol. I do have alot of aches on the weeks I have carbo with it. Anyway good luck to your sil.

    Also wanted to add that a port is not necessary for taxol. I get all my treatments through a regular IV every week.
  • KathiM
    KathiM Member Posts: 8,028 Member
    Taxol was part of my BC treatment...
    Adriamycin, Cytoxin, Taxol....

    Taxol is from the Yew Pine bush. In The Netherlands, this bush is used as a hedge for castles, etc. In one part of Holland, a company trims those hedges for free in exchange for the material that will supply one year's worth of medicine for all of Holland's needs.

    I had an allergic reaction on my first infusion, but this is quite common, and they were standing by with an antihistamine. Instead of stopping (I was hoping), they just stretched out the infusion...6 hours my last one took...

    Adriamycin knocked my socks off (and my hair!). Lovingly nicknamed the "red devil". But

    The taxol was much easier as far as side effects....

    Hugs, Kathi
  • herdizziness
    herdizziness Member Posts: 3,624 Member
    KathiM said:

    Taxol was part of my BC treatment...
    Adriamycin, Cytoxin, Taxol....

    Taxol is from the Yew Pine bush. In The Netherlands, this bush is used as a hedge for castles, etc. In one part of Holland, a company trims those hedges for free in exchange for the material that will supply one year's worth of medicine for all of Holland's needs.

    I had an allergic reaction on my first infusion, but this is quite common, and they were standing by with an antihistamine. Instead of stopping (I was hoping), they just stretched out the infusion...6 hours my last one took...

    Adriamycin knocked my socks off (and my hair!). Lovingly nicknamed the "red devil". But

    The taxol was much easier as far as side effects....

    Hugs, Kathi

    Interesting
    You know what I love about this site? Is not only the wonderful people but the bits of information that comes with them. I really find it interesting about the Yew Pine bush, and the company trimming and etc., how cool is that to learn something new? Thank you Kathi, I really enjoyed that.
    So the neuropathy is common in taxol I assume?
    We were in the Sierra mountains when she was telling my husband her chemo routine and Taxol was the only thing he came away with, so don't know if it's a combo thing or not.
    Thank you everyone for your input, it is much appreciated!!
    Winter Marie
  • herdizziness
    herdizziness Member Posts: 3,624 Member
    ktamp said:

    I'm on carbo and taxol for
    I'm on carbo and taxol for ovarian cancer. I get the carbo every 3 weeks and taxol every week. The carbo seems to be the bigger evil of the two drugs. I have two bad days after my chemo. I get chemo on wednesday and friday and saturday are my bad days. Mainly I am fatigued on the taxol. I've had no nausea with it. I'm starting to get neuropathy in my hands and feet after my 5th treatment. I take vit b 6 100mg three times a day which does help with the neuropathy. This was recommended by my oncologist although there is no research that I know that supports it. They have found that it helps and it seems to be helping me. It seems to be worse when I miss a dose. My hair bit the dust after 3 weeks. I've got a wig but I'm more self conscious with it. I'm always afraid it is going to move around and be on crooked. So I just wear turbins and scarves. It's more comfortable and I'm over being self conscious about not having hair. It is what it is. I've got all sorts of scarves and caps. Taxol is very hard on the bone marrow when given weekly. I've missed one treatment for low wbc counts and they had to lower my dose with my last treatment. I get neupogen shots 3 days a week to help boost my count. The neupogen is by far worse than the taxol IMO. It gives me lots of bone aches. Otherwise I've had very little aches with the taxol. I do have alot of aches on the weeks I have carbo with it. Anyway good luck to your sil.

    Also wanted to add that a port is not necessary for taxol. I get all my treatments through a regular IV every week.

    Thank you
    I'll have to ask her about how often she will get her infusions.
    I was wondering about the neuropathy in particular, she loves to knit and I was wondering if that was going to affect her.
    Winter Marie
  • herdizziness
    herdizziness Member Posts: 3,624 Member

    I did carbo-taxol..
    so my experience may be a bit different because of the combination of drugs. But overall, it was an easier treatment than the FOLFOX I did first. Worst part of it was losing my hair (and that is a side effect of both drugs, so pretty much a given). Getting prepared ahead of time with a wig and some cute scarves (she should check out the beaubeau website..really stylish pre-tied scarves that I still wear even tho I now have hair). The neuropathy can get bad-where I was treated all patients on this regimen were told to take glutamine powder daily to help with this. And aches and pains can develop, as taxol in particular damages joint/muscle cells. That was my most problematic physical symptom. I took ibuprofen and hydrocodone, which helped. The nausea for me was mild, taking the occasional Ativan was sufficient. Hope this helps! I'll be thinking of your SIL, hoping for the very best. Ann

    Ann
    Thanks Ann, I'll order her a couple of cute hats to wear in advance.
    Winter Marie
  • coloCan
    coloCan Member Posts: 1,944 Member

    Interesting
    You know what I love about this site? Is not only the wonderful people but the bits of information that comes with them. I really find it interesting about the Yew Pine bush, and the company trimming and etc., how cool is that to learn something new? Thank you Kathi, I really enjoyed that.
    So the neuropathy is common in taxol I assume?
    We were in the Sierra mountains when she was telling my husband her chemo routine and Taxol was the only thing he came away with, so don't know if it's a combo thing or not.
    Thank you everyone for your input, it is much appreciated!!
    Winter Marie

    ......also, just read about something being developed by US Army
    that you might want to look into, a vaccine called NeuVax-75 that "significantly reduces the recurrence of {breast| cancer and could, with more work, eventually help prevent colon, prostate and lung cancer altogether......"
  • KathiM
    KathiM Member Posts: 8,028 Member

    Interesting
    You know what I love about this site? Is not only the wonderful people but the bits of information that comes with them. I really find it interesting about the Yew Pine bush, and the company trimming and etc., how cool is that to learn something new? Thank you Kathi, I really enjoyed that.
    So the neuropathy is common in taxol I assume?
    We were in the Sierra mountains when she was telling my husband her chemo routine and Taxol was the only thing he came away with, so don't know if it's a combo thing or not.
    Thank you everyone for your input, it is much appreciated!!
    Winter Marie

    Lovingly called the 'Taxol tingles'...
    Yup, at least for me, Winter Marie....my fingers and toes tingled. I drank at least 2 quarts (4 quarts always my goal) per day the day before, day of, and day after infusion...after the ACT, and the carboplatin and 5FU for the rectal cancer, I came away with the only permanent numbness in my next to small toe on my left foot...

    Hugs, Kathi
  • KathiM
    KathiM Member Posts: 8,028 Member
    coloCan said:

    ......also, just read about something being developed by US Army
    that you might want to look into, a vaccine called NeuVax-75 that "significantly reduces the recurrence of {breast| cancer and could, with more work, eventually help prevent colon, prostate and lung cancer altogether......"

    Isn't it grand...
    That we all are the pioneers for the next generation of cancer treatments?

    My sister, recently dx'ed with her second cancer, breast cancer, tells me the new thinking there is that the sentinel nodes are removed, but no more, during surgery. Depending on the results of the nodes, the 'next set' (I had removed during surgery, because the pathology was back from the sentinels while I reclined on the surgery table) will not be removed, but radiated in place, if the path tests positive...outcomes are the same, research is showing, and this is less invasive and a bit more conservative as far as lymphodema is concerned...

    Hugs, Kathi
  • herdizziness
    herdizziness Member Posts: 3,624 Member

    Interesting
    You know what I love about this site? Is not only the wonderful people but the bits of information that comes with them. I really find it interesting about the Yew Pine bush, and the company trimming and etc., how cool is that to learn something new? Thank you Kathi, I really enjoyed that.
    So the neuropathy is common in taxol I assume?
    We were in the Sierra mountains when she was telling my husband her chemo routine and Taxol was the only thing he came away with, so don't know if it's a combo thing or not.
    Thank you everyone for your input, it is much appreciated!!
    Winter Marie

    OMGosh
    I can't believe that t r i m m i n g was considered a "bad" word. LOL. For anyone wondering, it wasn't a cuss word it was t r i m m i n g.
    Winter Marie
  • KathiM
    KathiM Member Posts: 8,028 Member

    OMGosh
    I can't believe that t r i m m i n g was considered a "bad" word. LOL. For anyone wondering, it wasn't a cuss word it was t r i m m i n g.
    Winter Marie

    And, yet....
    'Trims' was not....sigh...darn computers...

    Maybe r i m m i n g? Yup, that is what got you...I have no idea what it means, tho I don't want to know....

    I can't imagine you saying any 'bad' words, dearheart!!!

    Hugs, Kathi