I think I am done.

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  • Elarsen
    Elarsen Member Posts: 9
    #22
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    sofarstillhere said:

    Brac 2
    Hi, I am also brac 2. I was diagnosed
    Sept. 2002. I don't know where you can find the information, but if you are brac 1 or 2 you generally respond better to chemo. I hope this will be what will happen with your wife. Let us know what you find out about the parp Inhibitors. Thanks, Patty

    Parp's
    Here are some clinical trials that are going on:

    http://clinicaltrials.gov/ct2/results?term=ovarian+cancer+parp

    Our gyno-oncologist thinks they are about 2 years from full approval. The cells use many repair mechanisms when DNA splits improperly, but BRCA 1 & 2 mutations use a "back-up" system that these new drugs can target specifically. They are also finding that they work for non-BRCA 1 & 2 mutation sufferers.

    Here is a good overview link. It is for breast cancer but concept is the same :)

    http://breastcancer.about.com/od/targetedbiologictherapies/p/parp_basics.htm

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