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5FU Toxicity Treatment & Survival

Posts: 1
Joined: Aug 2012

I have a dear friend in a Southern California hospital being treating for 5FU toxicity either due to DPD deficiency or overdosing of 5FU. Severe toxic symptoms appeared after 2nd chemo treatment, then endured 3rd chemo treatment, then admitted to hospital one week later. Has been in the hospital now for 2 weeks, not getting any better (constant diahrea) and growing weaker each day. Need referral to expert(s) who treat or are knowledgable about ongoing toxic symptoms to 5FU or any other advice regarding treatment and survival. Thank you.

Posts: 3
Joined: Sep 2013

i went through the same thing here in colorado 4 years ago. it was an overdose. high doses of magnesium helped. i had 2 stays in icu/ccu oncology ward. still not well. lots of nerve damage, etc. good luck to you and prayers as well.


Posts: 2
Joined: Aug 2014

I am recovering from a severe toxic reaction to 5FU in my colon cancer chemo. I had a severe cardio reaction which I now read online is a well-odcumented (though rare) event. I also read that there are tests available to screen for it. Are there other people who were given the screening test by their oncologists? Was my oncologist negligent? I am told by my cardiologist that I have permanent heart damage.

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