My clinical trial update

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peterhw
peterhw Member Posts: 69
edited March 2014 in Colorectal Cancer #1
After 8 treatments of the clinical trial chemo, today I have my second CT scan. The result looks very good. The nodules in my lung are stable. No evidence of interval growth or new nodules. The lesions in my liver are smaller as compared to the previous CT scan done 5 weeks ago. The bigger lesions decrease about 30% in size. Couple smaller ones completely disappeared. I am very happy that the clinical trial is still working for me. Tomorrow I will start the 9th treatment.

The chemo drugs I am given are Sorafenib, Erbitux and Irinotecan. The interesting thing is I am KRAS mutated. But this trial recruits both wild type and mutation type. I am just lucky to be in this group. The research doctors need to analyze all the data after the trial is closed to see why it works for me. Their hypothesis is that the combination of Sorafenib and Erbitux may work for some KRAS mutated patient. If that proved to be true, it will make us KRAS mutants very happy.

Peter
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  • chicoturner
    chicoturner Member Posts: 282
    #2
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    clinical trials
    Hi Peter, What wonderful news! Your good news is just what I needed to hear! I am waiting to get to UCSF as I too am KRAS mutant and have only been holding my own. Where are you doing your trials. How are your side affects and where are your tumors? Thanks so much for sharing and I will pray that your success continues. Jean
  • peterhw
    peterhw Member Posts: 69
    #3
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    chicoturner said:

    clinical trials
    Hi Peter, What wonderful news! Your good news is just what I needed to hear! I am waiting to get to UCSF as I too am KRAS mutant and have only been holding my own. Where are you doing your trials. How are your side affects and where are your tumors? Thanks so much for sharing and I will pray that your success continues. Jean

    Clinical Trial
    Hi Jean,

    I have the clinical trial done at Johns Hopkins Cancer Center. The side effects are hair loss, diarrhea and the famous Erbitux rash. But they can be easily controlled by medicine. My primary tumor is in rectum which has been removed by surgery, mets to right lobe of liver and both lung.

    Peter
  • sfmarie
    sfmarie Member Posts: 602
    #4
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    Peter
    This is great news! I have been following your journey. And this sounds like such a great positive uplifting hopeful piece of news.

    I am wondering, since my sister may need to do a clinical trial, did your current onc. recommend this or did you do this on your own?

    Marie
  • coloCan
    coloCan Member Posts: 1,944 Member
    #5
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    sfmarie said:

    Peter
    This is great news! I have been following your journey. And this sounds like such a great positive uplifting hopeful piece of news.

    I am wondering, since my sister may need to do a clinical trial, did your current onc. recommend this or did you do this on your own?

    Marie

    Peter!! happy to hear you're getting good results
    with your current drug mixture. .....AS an added bonus, it may help others as well.....steve
  • Kathleen808
    Kathleen808 Member Posts: 2,342 Member
    #6
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    Peter
    Peter,
    Thanks for sharing your good news. We all like to hear when a new drug is working. Thinking of you.

    Aloha,
    Kathleen
  • Crow71
    Crow71 Member Posts: 679 Member
    #7
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    Okay Peter - This sounds
    Okay Peter - This sounds good. Thanks for the update. Congrats on good progress from a fellow KRAS mutant.
    Roger
  • AnneCan
    AnneCan Member Posts: 3,673 Member
    #8
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    Hi Peter,
    I am so happy for
    Hi Peter,

    I am so happy for you! I have been wondering how you are doing on this clinical trial; thanks for updating us + good luck with the rest of your treatments.
  • tootsie1
    tootsie1 Member Posts: 5,044 Member
    #9
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    Good!
    I was wondering about you,and I'm glad to hear some good news. Keep us posted!

    *hugs*
    Gail
  • peterhw
    peterhw Member Posts: 69
    #10
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    sfmarie said:

    Peter
    This is great news! I have been following your journey. And this sounds like such a great positive uplifting hopeful piece of news.

    I am wondering, since my sister may need to do a clinical trial, did your current onc. recommend this or did you do this on your own?

    Marie

    Finding clinical trial
    Hi Marie,

    Before my clinical trial, I had visited Sloan Kettering, UPMC, Georgetown and Johns Hopkins for second opinion. I decided to go with Johns Hopkins because they seem to have a lot of clinical trials available. My first clinical trial failed, but they were able to find another one for me in about 6 weeks. The other place to look for clinical trial is NCI (National Cancer Institute) at NIH. I have friend doing clinical trial there. She seems to be very happy about NCI. And the treatment at NCI is free of charge.

    Peter
  • robinvan
    robinvan Member Posts: 1,012
    #11
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    Hi Peter
    It's good to hear from you. I was wondering how you were doing. Hoping for continued good results.

    Be well... Rob; in Vancouver
  • Kathryn_in_MN
    Kathryn_in_MN Member Posts: 1,252 Member
    #12
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    thanks for sharing
    Thanks for sharing your good news! I'm so glad to hear this trial is working well for you!
  • Shayenne
    Shayenne Member Posts: 2,342
    #13
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    Kathryn_in_MN said:

    thanks for sharing
    Thanks for sharing your good news! I'm so glad to hear this trial is working well for you!

    Hi Peter!
    I'm so glad this treatment sounds good. Clinical trials have always scared me, as I felt like they would use me as a guinea pig to test me, not knowing what the outcome will be, but then again, without people going through these tests, we wouldn't know what these meds would do for us. One could be the cure! and I have great respect for those people doing these trials, thanks for it! I hope it continues to do well, as there is hope in our future!

    Hugsss!
    ~Donna
  • maglets
    maglets Member Posts: 2,576 Member
    #14
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    Shayenne said:

    Hi Peter!
    I'm so glad this treatment sounds good. Clinical trials have always scared me, as I felt like they would use me as a guinea pig to test me, not knowing what the outcome will be, but then again, without people going through these tests, we wouldn't know what these meds would do for us. One could be the cure! and I have great respect for those people doing these trials, thanks for it! I hope it continues to do well, as there is hope in our future!

    Hugsss!
    ~Donna

    that sounds good
    that sounds good Peter....hoping for continuing good news....

    Mags
  • geotina
    geotina Member Posts: 2,111 Member
    #15
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    Peter
    Congratulations on your sucess and I wish you continued success in your journey. You are paving the way for future treatments and you are to be commended for doing so. Again, I wish you nothing but continued success. Please continue to check in with us. Tina
  • Paula G.
    Paula G. Member Posts: 596
    #16
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    Great news. Keep us posted.
    Great news. Keep us posted. I'm happy for you Peter. My husband is KRAS mutant! Paula
  • angelsbaby
    angelsbaby Member Posts: 1,165 Member
    #17
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    Paula G. said:

    Great news. Keep us posted.
    Great news. Keep us posted. I'm happy for you Peter. My husband is KRAS mutant! Paula

    Peter
    that is wonderful news , I too am happy for you

    michelle
  • Fight for my love
    Fight for my love Member Posts: 1,522 Member
    #18
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    Hi Peter,I just read your
    Hi Peter,I just read your yahoo blog.I am so happy that your clinical trial has been going so well.It's like a miracle.I am sorry that you lost lots of hair,but you are a gentleman anyway.From your blog,I can see that you are still very positive and optimistic.This is really good and important.Keep your faith and keep fighting,you will win very soon.Wish you the best.Take care.
  • mom_2_3
    mom_2_3 Member Posts: 953 Member
    #19
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    Fantastic news
    What fantastic news Peter. I am so glad that you are getting such fabulous results from the trial and that you are able to control the side effects.

    Best thoughts to you,
    Amy
  • lisa42
    lisa42 Member Posts: 3,625 Member
    #20
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    glad
    Hi Peter,

    I'm glad to hear your update and that the trial meds are working well for you! I, too, am kras mutated, so I will keep this in mind as a possibility in my future, if the gemzar doesn't work for me (but I'm praying that it will).

    Glad to hear from you- I had been wondering how you were doing.
    Hang in there!

    Lisa
  • sfmarie
    sfmarie Member Posts: 602
    #21
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    peterhw said:

    Finding clinical trial
    Hi Marie,

    Before my clinical trial, I had visited Sloan Kettering, UPMC, Georgetown and Johns Hopkins for second opinion. I decided to go with Johns Hopkins because they seem to have a lot of clinical trials available. My first clinical trial failed, but they were able to find another one for me in about 6 weeks. The other place to look for clinical trial is NCI (National Cancer Institute) at NIH. I have friend doing clinical trial there. She seems to be very happy about NCI. And the treatment at NCI is free of charge.

    Peter

    Thank you
    Peter for responding to my post. I sent it along to my sister and I know your story and journey will give her HOPE.

    I am praying this is a silver bullet for you! Keep us all posted.

    Marie

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