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3-Bromopyruvate

CANCERFIGHTERS4EVER
Posts: 4
Joined: Dec 2013

Hi all, just a heads up that clinical trials on 3-bromopyruvate(3-BrPa) have begun, & are scheduled to move forward at a significantly fast pace. The company, PreScience Labs, has received fda IND approval to begin human trials, and said trials were scheduled to begin recruiting patients as of Jan 2014.

 

Hopefully, this will be the beginning of a new age in curing or at least treating breast, lung, pancreatic and ovarian cancers with long term remission as the goal in the not too distant future.

jbashin
Posts: 1
Joined: Aug 2014

Hi my husband was interested in finding this option do you know where we can find out how to apply for this?

CANCERFIGHTERS4EVER
Posts: 4
Joined: Dec 2013

Well at least there's been some movement in the U.S. wrt this compound, with some seemingly promising results thus far in use for pancreatic cancer

http://www.presciencelabs.com/cancer-treatment-progress/clinical-development.php

http://www.ncbi.nlm.nih.gov/pubmed/25326230

 

Phase I human clinical trials  set to begin by Jan.-Feb. 2015

jjmca
Posts: 1
Joined: Mar 2016

I know the posts above are a bit dated compared to my response, but I just finished a book, "Tripping over the truth" by Travis Christofferson.  The author lays out the almost discarded metabolic theory of cancer.  The theory is close to 100 years old.  Essentially when the cell mitochondria become damaged the cell turns to a more ancient form of producing the body's energy, ATP.  The cancerous cells express a variant, hexokinase II, of a healthy cell compound hexokinase.  Hexokinase II shuts down the natural signaling of cell death, hoards ATP for replication of the cancerous cell and prevents the toxins that the cancerous cell produces (lactic acid) from accumulating inside the cell.  What 3-bromo pyruvate (3-BP) does is inhibits hexokinase II preventing the release of these toxins from the cell.  The cancerous cell ends up poisoned by its own waste products.  Hexokinase II is found in almost all cancer cell types according to research highlighted by the author, not in healthy cells.  3-BP therefore only kills the cancerous cells and has no effect on healthy cells and, apparently, has no toxicity to the body in general.

Searching for a friend suffering from cancer I found one clinic the Dayspring Cancer Clinic in Scotsdale, Arizona that is using the protocol of the discoverer of 3-BP's effect, Dr. Young Hee Ko, to treat their cancer patients.  There might be others. When Ko first dicovered the 3-BP effect she said she had to repeat the in-vitro experiment 100 times to convince herself of how fast it was killing the cancer cells.  It blew away standard cancer chemo drugs.  Hope this helps someone.

 

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