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Erbitux resistance

Hooley's picture
Hooley
Posts: 149
Joined: Aug 2012

Anyone had resistance to this drug if so  what were signs. How long had u been on it. And what was your next option

Goldie1's picture
Goldie1
Posts: 250
Joined: Sep 2011

Was the combo my husband Pat was on for 5 months.  Unfortunately, he did not have any postive results during that time.  His next option was Folfiri & Avastin with the 5 FU continuous pump infusion every other week.  He faired pretty well on this for 8 months, some shrinkage and less density in the lesions in both the liver and the lungs.  When that no longer worked, he was put on the oral med, Stivarga (regorafenib) which he has been taking since last Nov.  CT scan in 2 weeks to see if it is working.  If not, on to a clinical trial.

Take care,

Ellen

PhillieG's picture
PhillieG
Posts: 4667
Joined: May 2005

I've been on Erbitux for about 6-7 years. It's done a very good job as far as keeping my lung mets growing slow. I haven't gotten to the "next option" part yet...

Hooley's picture
Hooley
Posts: 149
Joined: Aug 2012

Wow,Phil, that long!!! Fantastic.  Do u have chemo with it also?   Do u take any other stuff eg medical or natural? Or off amything

serenity101's picture
serenity101
Posts: 80
Joined: May 2013

I was on erbitux and irinotecan for only a couple of months and a new tumor showed up in my liver, although I believe my other liver mets pretty much stayed stable. My next option was regorafenib.

Hooley's picture
Hooley
Posts: 149
Joined: Aug 2012

Yeh I'm in same boat 

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