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PSA Finally Under 1

Posts: 634
Joined: Mar 2010

Well, 2 years and 9 months following CyberKnife treatment i n Sep 2010 (and widely varying PSA readings since then), my PSA score has finally dropped under 1 at 0.995!!!  That's only 5 1000th's under 1 but it's under 1 just the same.

Here's a(nother) recap of the history of my PSA readings since I received treatment:

12/15/10 -- 9.48

03/23/11 -- 3.03

06/14/11 -- 5.07

06/20/11 -- 3.72

09/12/11 -- 3.56

12/23/11 -- 1.81

03/26/12 -- 1.55

06/23/12 -- 1.69

09/14/12 -- 2.12

12/13/12 -- 1.26

03/25/13 -- 1.41

06/25/13 -- 0.995


My RO thinks we can switch to 6 month testing now.  I'm still a little worried about the lack of consistency in the test results but I'm tired of worrying about it.   Depsite the spikes, the trend is generally downward and, after receiving a clean MRI/MRSI scan in Oct 2012 (after the 3 increasing PSA scores), I'm confident that the cancer is gone and that I can switch to semi-annual testing.  So, next test will be due around Xmas this year.

BTW, I had double hernia surgery in May and I've pretty much recovered from that already.  After a week of some significant discomfort, most of the pain is gone. Still have to lay off strenuous exercise for another month or so but I can already do 90-95% of the things I did before.   I also got 3 cortisone shots in my spine & right scroliliac joint to alleviate some back/hip pain.  That pain is pretty much all gone too.

PS: The urinary bleeding that I was experiencing a couple of months ago resolved itself and went away on it's own after had a cytoscopy in March.  The urinary frequency/urgency was reduced after I started Flomax around the same time but I still have to resort to a pee bottle from time to time and, as expected, the Flomax eliminated most of my ejaculate flow but I'm learning to live with that.  At least, I can get still get an erection and "come" (even if it almost entirely dry).

Hopefully, this will be the end of my medical problems for awhile.  Keeping my fingers crossed on that!





VascodaGama's picture
Posts: 1544
Joined: Nov 2010


Good news indeed.

The fact is to be celebrated. How about a trip to Europe to keep the moment unforgetful ?

SmileEmbarassedKissSealedLaughingTongue OutMoney Mouth  



Note: Regarding your trouble with the Scroliliac joint, I have been reading about the influence that the spine could have in our health if affected by the cancer. In other words, what symptoms could we have that would related to the affected bone. So far I have identified two parts that could be due to spread in my case. The L2 and the L5.
Here is an interesting graphical of the symptoms; http://www.chiroone.net/why_chiropractic/index.html


VG  Wink

Posts: 634
Joined: Mar 2010

Thanks, Vasco!

Funny you mention Europe.  I "met" a woman on Match who lives in Bedar, Spain not far from where you live in Portugal.  Was thinking of visiting her there this fall until I actually met her and found her to be quite a pill but I am still interested in visiting that part of the world and perhaps we'll cross paths one of these days.

BTW, my S/I joint and back problems were caused by excessive weight that I attempted to "squat" while weight lifting.  However, when they CAT scanned the region, the spine specialist also found deformities in my L4/L5 which she may have also contributed to the pain.  So, when the S/I shot didn't do the job, she hit the L4/L5 vertebrae in my spine too and that actually seemed to do the job.  Fortunately, no indication of cancer there.

Posts: 2
Joined: Dec 2013

Had C/K June 2012 , PSA 16 .

Jan. 2013 / 4.25 , Oct. 2013 / 4.61 . Concerned about both the rise and the still hi numbers . R/O said no problem , to just wait . Hoping he's right . 

Posts: 634
Joined: Mar 2010


Like you, I was concerned about the slow rate of decline in my PSA numbers and it took "forever" for my PSA level to drop below 1.   My PSA has sinced dropped even lower and you can find a further discussion about that in this thread: http://csn.cancer.org/node/265310.

Based on my experience, the main thing to be concerned about is any consecutive increase in your PSA numbers.  An increase twice in a row (in any amount) is an indication of treatment failure and addtional testing should be done to determine if there's still cancer in your prostate or not.

In my case, I had 2 increases in March & June 2012 and had a combined MRI/MRSI (magnetic imaging AND magnetic spectroscopy), which is a very sophisticated test which uses a Tesla magnet inserted in the rectum in conjuction w/the regular MRI scan, to determine if there was still any cancer in my prostate.  The MRSI is able to measure the amount and location of choline, which is a marker for cancer, in the prostate.  No cancer specific amounts of choline were found in mine. And, after my PSA dropped following the test, the conclusion was that the rise was due to a classic 1-2 year post radiation treatment "bounce" and not an indicator of treatment failure.

Assuming there is no concern about treatment failure, it can take as long as 3-4 years for your PSA to drop to "acceptable" levels following radition treatment.  What's "acceptable" varies but it's generally agreed that a PSA below 1 is a good measure of success and that a PSA level below .5 greatly enhances your probablility of 5-10 year post treatment survival.

Best wishes and good luck!



lewvino's picture
Posts: 1004
Joined: May 2009

Congrats on reaching less then 1!


Posts: 634
Joined: Mar 2010

Thanks, Lewvino:

If you missed it, here's the link to my 3rd Year status report, which reported an even lower PSA reading: http://csn.cancer.org/node/265310

ralph.townsend1's picture
Posts: 352
Joined: Feb 2012

Mike, That's great news, keep going down. Sorry I have not been around for while, been alittle under the weather.

best of luck, Ralph

Posts: 634
Joined: Mar 2010

One year following my 1st below 1 PSA reading, the trend is progressing nicely downward.  Here are the <1 results so far:

06/25/13: 0.995

12/17/13: 0.624

06/19/14: 0.416

I don't think I've reached my post-treatment "nadir" yet but the current result is very reassuring, since at least one study concludes that that a PSA nadir <.50 is indicative of a PSA disease-free survival rate of 75% and a distant metasisis-free survival rate of 97%. 

See: http://www.psa-rising.com/med/ebr/nadir_survivalpostrad06.htm

As mentioned in the article:

"While there is no magic number for the PSA that guarantees that prostate cancer has been cured in an individual patient, in general, the lower the PSA number, the better chances that the cancer will not return or spread," said Michael E. Ray, M.D., Ph.D., lead author of the study and a radiation oncologist at the University of Michigan Medical Center.

"In addition," Dr. Ray said, "the study showed that the longer time that the PSA continues to decline after radiation, the less likely the cancer will recur or spread."

So, it looks like the prospects for my continued post-CK treatment survival from PCa are very promising.  Smile






VascodaGama's picture
Posts: 1544
Joined: Nov 2010

It is nice to read about your good results. Probably you could change now the title of the thread to PCa Finally Under control.

Unfortunately there are no other marker yet today that we could use to certify cure. Though, the continuous drops in PSA make your prospects for post-CK treatment survival very promising of a cure.

I wonder if you need still more results to certify your rates. Probably now you could be looking for a comprehensive “cautious programme” to follow up your health as a non cancer patient. My advice is to get a gene profile and the levels of DHT under vigilance.
Kongo stopped being around since his last update, indicating a PSA level under the zero two decimal places (PSA=0.0X ng/ml) but his starting level at CK-treatment was lower than yours.

Best wishes for continued success. Enjoy.



Posts: 634
Joined: Mar 2010

Thanks for the suggests, Vasco.

Not sure what a genetic profile and DHT measurement will do for me at this point but I'll consider it.  I've actually noticed that Kongo has been pretty silent about his progress and missed his report of a single digit PSA reading.  He had a much better post treatment PSA history than I did and I've posted the specific results just to let others (with a similar history) know that there's hope even if your PSA results are erradict and slow to decline.

I'll continue to post in this thread over time until it looks like I've reached my nadir.  Doing this to also give others who have received radiation treatment a longer term outlook on what needs to be done to monitor treatment outcomes.  Currently doing semi-annual testing and will probably got to annual testing in the next year or so. 





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