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Doxorubicin

Tina Brown's picture
Tina Brown
Posts: 1054
Joined: Nov 2009

I know there is currently a shortage of Doxil (USA) Caelyx (UK) so when my oncologist prescribed Caelyx for me last week (How can he not know it had been discontinued - doh) his team managed to substitute it for a different Chemo - Doxorubicin.

I was told that it is similar to Doxil/Caelyx but doesn't have the coating on it that protects the heart and prevents hair loss.

So I was wondering if anyone out there had had this chemo and if so DID IT WORK? Its only been about 8 weeks since I finished Topotecan and I am feeling quite weary and nauseated on this drug.

Any imput will be greatly received. Love Tina xxxx

jt25741
Posts: 23
Joined: Apr 2012

My wife was going to go on Doxorubicin, but the Dr's obtained some other drug called Lipodox. It is the liposomal form of Doxorubicin, just like Doxil is (that pegylated coating you talked about). This not only protects the organs, but also may target the tumor better -- and lasts in the system longer with fewer side-effects. This way treatment schedules can be easier to tolerate. You may want to ask about Lipodox. It has very recently been allowed in the USA as a substitute for Doxil...not sure about the details of availability elsewhere.

Best wishes

Jim

Cynthia Rose's picture
Cynthia Rose
Posts: 35
Joined: Apr 2011

That is GREAT news there is a Substitute for Doxil! My Mom Has Stage 4 Uterine cancer and is Treated like Ovarian She is now on Carbo/Gezmar.

Cynthia Rose's picture
Cynthia Rose
Posts: 35
Joined: Apr 2011

That is GREAT news there is a Substitute for Doxil! My Mom Has Stage 4 Uterine cancer and is Treated like Ovarian She is now on Carbo/Gezmar.

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