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HOPE for glioblastoma!

I_Promise's picture
I_Promise
Posts: 208
Joined: Aug 2011

Yay for
ICT-107 Phase II Clinical Trial - FDA APPROVED!

The dendritic vaccine is making progress! There is HOPE,

Julia

mighty6
Posts: 47
Joined: Sep 2011

Julia and all,

This trial require patient's HLA-A1 r A2 to be positive, which exclude about 30% the GBM patients. but this is promising regardless. My husband is not qualified. but I hope all of others do. good luck!

madisonmuzz
Posts: 13
Joined: Apr 2011

I hope this is the answers a lot of us are praying for......

I_Promise's picture
I_Promise
Posts: 208
Joined: Aug 2011

I would have my own lab and arsenal of scientists. I would want to accelerate the research. I would make sure the cure is tomorrow and not in 20 years because I truly believe it is within our grasp.

Julia

I_Promise's picture
I_Promise
Posts: 208
Joined: Aug 2011

Movement toward Phase III trials is encouragingly on the horizon. The largest clinical trial investigating the use of DC vaccines to treat patients with brain tumors (DCVax®-Brain) is sponsored by Northwest Biotherapeutics.

jeffballew
Posts: 9
Joined: Apr 2010

it eliminates those who have already begun other treatments. Has anyone seen the Polio Vaccine treatment. it looks promising as well.

mighty6
Posts: 47
Joined: Sep 2011

you are right.
ICT-107 requires the consent before chemo
Dcvx-brain requires it even before surgery
TVI-brain -- needs to confirm

I don't know about Polio Vaccine, can you provide more info.?
thanks,
Jane

jeffballew
Posts: 9
Joined: Apr 2010

The Polio Vaccine is through Duke, where I get my treatment. I am a candidate, and i've had Temodar and Avastin.

you can google it but here are 2 urls
http://www.ncbi.nlm.nih.gov/pubmed/18766173

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881183/

my oncologist has high hopes once it passes the IRB. The viral technology is thought to stimulate the immune system to attack the tumor. There are actually polio virus receptors on the glioblastoma and the polio virus impregnates the tumor and it leads to a large inflammatory response.

I_Promise's picture
I_Promise
Posts: 208
Joined: Aug 2011

I will check it out

mighty6
Posts: 47
Joined: Sep 2011

Thanks for the reply. I did no notice it till now.
Did you get into this trial eventually? Hope things are going good with you. Do you know if that trial requires surgery to be done in Duke? My husband was dx. 3 months ago. he had surgery and 6-weeks radiation in another city.

thanks again. Jane

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