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Rise in ALT/AST during Avastin/Cytoxin treatment

Posts: 272
Joined: Jan 2011

I've been on 2 cycles so far of Avastin/cytoxin and my blood levels has been pretty good. I had blood taken at my primary care physician last week and the range with his lab for ALT was 7-52, mine came in at 56. He said it was still ok because it was only slightly over the top of the range. I noticed that the high and low lab ranges at MSK are always different.

Has anyone else had any increases in their ALT/AST while on chemo. I know when I was on Gemzar and even Carbo/Taxotere this happened. I was always told that once a person stops chemo it goes to normal. But, still it is concerning.

nancy591's picture
Posts: 1059
Joined: Sep 2009

I posted this maybe two weeks ago. My ALT and AST were both slightly elevated while on that combo. I was told it was from the cytoxin and the NP at MSKCC was not very worried. She told me sometimes they withhold treatment for a week to let the level come down. I am no longer on cytoxin. I go in on Thursday for my first taxol infusion. That will be about 2 wks post cytoxin so I will let you know if my level comes down.

Posts: 272
Joined: Jan 2011

Hi Nancy, thanks for the info. This is the first time it's been raised since I've been on Cytoxan/Avastin. I know in the past, oncologists, didn't seem to worry about this. I hope all goes well for you on the Cytoxan/Taxol infusion. I also appreciate you responding to me. I wish you the best of luck in your treatment.

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