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Modified Citrus Pectin

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

Guys, this would be especially important to our Stage IV folk. Please don't overlook this info!

Also, I'm trying to find the best brand to buy and know nothing about vitamin brands! I'm not finding this very easily, either. It has to be 'modified citrus pectin' because it isn't absorbed otherwise.

Effects of daily oral administration of quercetin chalcone and modified citrus pectin on implanted colon-25 tumor growth in Balb-c mice.
Altern Med Rev. 2000 Dec;5(6):546-52.

This study examines the effects of modified citrus pectin and QC on the size and weight of colon-25 tumors implanted in balb-c mice. Fifty mice were orally administered either 1 ml distilled water (controls), low-dose QC, high-dose QC, low-dose modified citrus pectin (0. 8 mg/ml) or high-dose modified citrus pectin (1.6 mg/ml) on a daily basis, beginning the first day of tumor palpation (usually eight days post-implantation).

A significant reduction in tumor size was noted at day 20 in all groups compared to controls. The groups given low-dose QC and modified citrus pectin had a 29-percent (NS) and 38-percent decrease in size, respectively. The high-dose groups had an even more impressive reduction in size; 65 percent in the QC group and 70 percent in the mice given modified citrus pectin.

This is the first evidence that modified citrus pectin can reduce the growth of solid primary tumors, and the first research showing QC has antitumor activity. Additional research on these substances and their effect on human cancers is warranted.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Modified Citrus Pectin should be considered as a key part in any preventive or therapeutic regimen for any type of cancer. Dosage is also speculative, but based on the animal studies, we believe that a dosage of five grams per day may provide significant preventive or therapeutic benefits.

Nutrition Review Citrus Pectin

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

These studies appear to show that MCP makes it difficult for cancer cells that break off from the main tumor to join together and grow in other organs. However, in most animal studies, MCP had no effect on the main tumor, suggesting that it may only be useful for preventing or slowing the growth of metastatic tumors in very early stages of development.

Recent laboratory studies of human and animal cells have provided information on how MCP might slow the spread of cancer. MCP appears to attach to galectin-3, a common chemical in many cells. Galectin-3 is present in abnormally high levels in many cancers and plays an important role in the growth, survival, and spread of cancer cells.

American Cancer Society and Citrus Pectin

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

I have a high school friend who is currently working in New York and New Jersey as a registered dietitian and fitness professional in private practice and for corportations. She's also teaching at the Alvin Ailey Dance Theater and Hunter College. NYU '96 master of science, Clinical Nutrition. She helped me out. Marie recommended the NOW brand of vitamins. I found it on Amazon for $30.00 less than online vitamin shops. I got a 30- 90 day supply for $56.56 with shipping.

jillpls's picture
jillpls
Posts: 241
Joined: Mar 2008

I too am taking MCP in pill form. I had a very bad chemo cycle at Christmas and landed in the er. so When I got out, I went to a homopathic dr and she said to take the MCP as well as theribotic powder. I am doing great now. My last Ct (2 wks ago) showed the ascities in the gut area was almost all gone and no new growth anywhere. With Gods blessing and the MCP I'll keep staying stong!
Jill

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

Maybe people think it sounds too simple but a new report said HIV can be helped by bananas so why not this?

I'm so glad to hear your news!

papajedi's picture
papajedi
Posts: 110
Joined: Oct 2009

Can you tell me where you buy your MCP ? How much do you take ?

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

I bought mine off Amazon.com and got the NOW brand which is one my friend recommended (she's got several majors in health, nutrition, etc). It was cheaper there than thru a vitamin store online.

I'm taking 1 tsp a day in applesauce, which is the amount recommended for maintenance. I don't have mets and my CEA is stable and within normal limits. Since your CEA is rising and you have some tiny bone mets, I would suggest you take the dosage recommended for those with active disease, which is 3 tsp a day, one tsp at a time.

It's not cheap! I paid over $55.00 and it will last me 3 months. If you take full dosage, it will last you one month.

Be sure to get the powder and be sure it's modified pectin!

papajedi's picture
papajedi
Posts: 110
Joined: Oct 2009

All my scans have been increasingly better to exceptional. The last one showed all bone mets gone except a tiny 1cm one, nothing lights up at all. My onc is puzzled, I've had isues with inflamations and now have arthritis in my shoulders so think that's what's causing the spike. Just had a scan apr 19th that was excellent........so what to think.

2bhealed's picture
2bhealed
Posts: 2084
Joined: Dec 2001

Hi Diane,

My Naturopathic doctor had me on this powder and explained how it worked like this:

The MCP is like spraying the invisible man (being the cancer cells) so that the body can see him (the cancer cells) and kill him off. The MCP adheres to the cancer cells and "exposes" them and the body can then pop them off. I'm probably not doing her explanation justice but it has been 8 1/2 years.....I don't remember the exact words.

I used the powder form and put in in my juice. If you need a distributor I can give you the name of my Naturopath. It was fractionated pectin.

It's a shame that this information is not commonly out there and that all cancer patients aren't put on this stuff. But that's why I am continuously encouraging folks to find a good Naturopathic doctor who is knowledgeable in cancer/nutrition.

peace, emily

thready's picture
thready
Posts: 475
Joined: Sep 2009

Diane,
Thank you for letting us know about this and Emily keep encouraging folks, we need all the information and help we can get! (I am asking if anyone knows why don't the oncologists know about this stuff. Do they not believe it will help? Just wondering)
Jan

Erinb
Posts: 295
Joined: Apr 2010

When we were interviewing surgeons, I asked about Pawpaw and other alternatives. He wouldn't comment on anything other than'standard medicine' because that was the area he was educated in.

Holdtight's picture
Holdtight
Posts: 138
Joined: Aug 2009

I am interested in finding out more - can you give me the name of the distributor you know. Thanks.

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

You would think 'shrunk by 70%' would get onc's attention! Maybe the fact that a patient can spend $56.00 a MONTH vs $32,000 has something to do with it. Ten years from now some studies will be completed and this will be made public yet how many will have died by then that this might have helped?

Emily, I read an explanation that said the modified fruit pectin coats the microscopic tumor cells so they cannot stick to each other and form tumors. In solid tumors, it coats the outside of the clump of cancerous cells so they cannot grow larger and they begin to starve off (think how Avastin works) and shrink. Our body will kill off the single cell floating around, unable to stick and grow.

Jan, You can't over dose on this stuff. It's good for you anyhow. One action is that it removes metals and pollution from our system. It might even help with neuropathy. The only side effect noted is some people can get constipated on massive doses.

Emily, several places I saw 'mix in warm water'. Do you think that's just to dissolve it?

shmurciakova's picture
shmurciakova
Posts: 910
Joined: Dec 2002

I just wanted to add that my N.D. also had me taking modified citrus pectin. I haven't taken it regularly for a while, but I think I will start again! Thank you for the post.
-Susan H.

mom_2_3's picture
mom_2_3
Posts: 937
Joined: Nov 2008

Thanks, I will add it to my regimen. Do you know what is best? Pill form or powder form mixed into water?

Thanks!

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

All the trials used powdered and my high school friend with a masters degree in science and nutrition said powdered mixed in water or juice.

She said NOW is a good brand and it was $30.00 cheaper on Amazon than any place I found!

sheri22
Posts: 278
Joined: Jan 2009

Diane
Thanks for this post I will definantly talk to DR about this and hope he okays it I dont see why he wouldnt as chemo isnt working right now anyways can I get it from anywhere
or will I need to order it Thanks again Sheri22

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

My friend with a masters in science and nutrition said she recommended the NOW brand. I found it on iherb but did a search and found it on Amazon.com for a lot less.

Sheri, the possibilities are amazing! It cannot hurt! It's the bitter portion of the fruit and it must be 'MODIFIED' because it won't pass through the intestines and into the bloodstream otherwise.

I'm going to use it to help prevent spread and hope and pray it works for you. It meant a lot to me that Emily uses it. I really respect her opinion.

Diane

scouty's picture
scouty
Posts: 1973
Joined: Apr 2004

Back when I was in the thick of my fight. It was the powder form and I mixed it in my juicing twice a day for almost a year after I stopped chemo. I was working so hard to keep my immune system at it peak form and hoped it allowed my WBC (white blood cells)to kill off the cancer cells like they were meant to.

Lisa P.

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

I wish all of our friends would look into this! My MCP is supposed to arrive in the mail by Monday at the latest. It did say 'warm water or liquids' and I'm wondering if that's only to insure it dissolves. I cannot find anything that says it works better that way. Do you know?

Thanks again for sharing. You're one of my heroes!

geotina's picture
geotina
Posts: 2056
Joined: Oct 2009

While this does sound very encouraging, I think, my own personal opinion, that we need a little caution when recommending supplements. Many of us are in the middle of chemotherapy treatments and most oncologists do not want us taking any supplements of any kind without their knowledge and approval. I have questioned George's oncologist a few times about this kind of stuff and he put it to us very plainly and patiently, if it strengthens regular cells what do you think it will do to your cancer cells. Now, if George were go to NED/NEAD I would be all over this stuff. In fact, I have been reading up on naturalpaths for this very reason. If you are NED, this is great information.

Now don't anyone get mad, I'm just putting it out there that you do need to check with your doctors if you are currently in treatment before adding supplements and the like to your daily routines.

Have a good one - Tina

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

Be sure to mix this in applesauce. It disappears in applesauce but nasty otherwise.

C Dixon
Posts: 202
Joined: Jan 2010

I ordered this. Thanks so much for the information.

Catherine

LivinginNH's picture
LivinginNH
Posts: 1295
Joined: Apr 2010

Hi Diane,

Thank you very much for this information! I'll mention it to his onc. tomorrow as well. It seems to be certainly worth a try! :-)

Take care,

Cynthia

C Dixon
Posts: 202
Joined: Jan 2010

OK, thanks again for posting this. I got mine yesterday and I remember you saying 5 grams but when I double checked online several site said 5mg 3 x a day. Is that what you are doing? I ordered the Source Naturals Pecta Sol brand and it has no taste in water. I hope that doesn't mean it isn't effective. I drink plenty of yuck and am happy not to add to it but will if I need to.

Catherine

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

3 times a day if you have tumors and once a day for maintenance. I'm taking only 1 tsp (5 grams) in applesauce at night. I can't taste it or 'feel' it in the applesauce.

Lisa P. (Scouty) took it twice a day and I think Emily (2bhealed) did also. Both are way out and healed!

Modified Citrus Pectin should be considered as a key part in any preventive or therapeutic regimen for any type of cancer. Dosage is also speculative, but based on the animal studies, we believe that a dosage of five grams per day may provide significant preventive or therapeutic benefits.

dianetavegia's picture
dianetavegia
Posts: 1953
Joined: Mar 2009

Here's that info! Note that both Scouty, Jill, Susan H. and 2bhealed took or take this. Catherine and I started it just recently.

C Dixon
Posts: 202
Joined: Jan 2010

took mine this morning and going to take another after I finish my strawberries!

Catherine

SueRelays
Posts: 489
Joined: Dec 2009

My dietician recommend MCP to me prior to my liver resection. i was taking it 3x a day, but just one now. It is a pretty HOT commodity....as many places were out of it!!! I paid $110.00 for it, so THANKS Diane for sharing!!!

lisa42's picture
lisa42
Posts: 3663
Joined: Jul 2008

Thanks, Diane, for posting this. I believe you posted it a while back also, and I had forgotten about it. One thing I'm wondering... if it coats the cancer cells and doesn't allow them to stick together, does that coating act as a barrier to the chemotherapy I'm on? I have a feeling I won't get an accurate answer from my onc, as he's leary of supplements, so i wonder how I'll know. The last thing I want to do is render my chemo ineffective, but I'd like to take it along with the chemo if it will work. As a stage IV patient, I'm too afraid to rely solely on someting like this without the chemo, as it's just recently that I've gotten my first "stable" PET scan report (wheras there was cancerous growth in the two prior scans).
My other question, Diane- you said you mix it in applesauce to disguise the nasty taste. Yet you say the directions say to dissolve it in warm water. Do you not mix it in water, but just sprinkle it in the applesauce?

As to other supplements, I currently also take cimetidine 800 mg/day, resveratrol (red grape seed extract), and I alternate between aspirin and tumeric (I read the tumeric needs to be taken with a dash of black pepper, mixed in olive oil). I've had to cut back on the tumeric/aspirin because I was starting to develop bruises all over (it can cause increased bleeding). Now that I have just been put back on Avastin (along with Gemzar and Xeloda), I will need to be careful about anything that can increase my bleeding.

I will look more into the modified citrus pectin. Diane- do you also take the quercitine chalcone, talked about in the first study mentioned, along with the MCP?

Lisa

Scambuster's picture
Scambuster
Posts: 975
Joined: Nov 2009

Just thought it a good idea to bring this post back to the Top re MCP (Modified Citrus Pectin)

You can buy it online through discount Supplement sites. I get mine from the US online and they ship to my door over here in China.

I take 1 heaped teaspoon every day on my health shake which I pour over cereal + fruit. Easy.

Best to all Scam

Scambuster's picture
Scambuster
Posts: 975
Joined: Nov 2009

Just thought it a good idea to bring this post back to the Top re MCP (Modified Citrus Pectin)

You can buy it online through discount Supplement sites. I get mine from the US online and they ship to my door over here in China.

I take 1 heaped teaspoon every day on my health shake which I pour over cereal + fruit. Easy.

Best to all Scam

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3915
Joined: Nov 2010

been on this 2 months. Not on chemo days.
great post by the way.
Forgot to check with onc. I know her answer.
No clinical study prefer not. But then she knows my approach and smiles.
Was advised by naturopath. Study is interesting.
Was doing this anyway but it nice the mice made it.
Hopefully we all will too.

Love pete

ps thanks scam. He told me about this independent of naturopath.
I like getting good tips from a range of sources.

GaryinUK
Posts: 63
Joined: Feb 2011

Scam

I am in the UK, I can see MCP for sale on Amazon but when i looked at the contents of the bottle only a small proportion was actually pectin, most of the rest being sodium or pottassium, is that what your stuff consists of or is it pure?

Anyone chip in here

Gary

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3915
Joined: Nov 2010

hi gary,

good question, never read the packet before.
mine is a naturopath only brand.
I presume its the best she knows about as she is focused on my bowel cancer.
this stuff tastes horrid, but if it tastes bad it must kill those little micro mets ? hey
only joking, we cannot take our supplements or this whole battle to seriously.
its only our lives on the line. and thats the key I think.
I have my my pectin straight but today I am up early and wuill have it in juice.

cheers,
Pete

http://www.bioceuticals.com.au/product.aspx?function=displayproduct&productid=269

BioPectin 250g powder

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250g

AUSTL: N/A

BioPectin contains hydrolysed pectin derived from citrus fruits. Pectin is a natural source of fibre.

Each Serving (5g) Contains:*
Energy
41.1kJ (9.85Cal)

Protein
245mg

Fat - total
0g

- saturated
0g

Carbohydrate - total
1.5g

- sugars
1.5g

Dietary fibre
2.85g

Sodium
70mg

Calcium
5mg

Hydrolysed citrus pectin
5g

* Based on average amounts.

GaryinUK
Posts: 63
Joined: Feb 2011

Pete

Thanks, that matches what is on the label of the brand we are purchasing

Gary

Buckwirth's picture
Buckwirth
Posts: 1272
Joined: Jun 2010

But as I have it figured, to get the effect of the high dose pectin you would need to consume 3.8oz a day if you weigh 150lbs.

A couple of teaspoons on your cereal in the morning ain't going to cut it.

John23
Posts: 1832
Joined: Jan 2007

You sure put a lot of faith into the "industry's" answer to cancer, ehh?

Why are you so hell-bent on knocking anything else that might do the job?

(Just curious, and not meaning to be argumentive...)

Best of health to you,

John

Buckwirth's picture
Buckwirth
Posts: 1272
Joined: Jun 2010

All I did here was convert the dosing, of course admitting my conversions could be wrong. Not exactly a simple formula, and I am working on an iPad. Mg to pounds, pounds to an average human weight, back to grams then to ounces... Kind of makes the head spin.

You're not of the opinion that the dose for a mouse would be appropriate for a human are you?

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3915
Joined: Nov 2010

good morning graci,

loved your reply.

just fyi
my bio pecin says to sprinkle on cereal or add to juice.

I'll add it to my juice.

what a wonderful post that highlights the benefits of vegetable based lifsytle.
now maybe I can have my organic bacon once per week and some pectin each day.

hugs,

Pete

John23
Posts: 1832
Joined: Jan 2007

There had been a time in my life that I was as cynical as you!
Now not as much so, but I still habitually question everything,
and always look for what "makes sense" in claims made.

Sometimes though, things may not "make sense", but still be
as valid as anything that's been "scientifically proven".

I haven't formed an opinion of "modified citrus pectin", not that
my personal opinion should matter...... however...

I'm sure you've heard about Homeopathic medicine?

The compounds are so diluted, that there isn't a trace of the
original ingredient after the dilution process. There is absolutely
no "scientific data" that would indicate that any homeopathic
substance can possibly be of value biologically.

Homeopathic compounds have been described by the well educated,
as being nothing more than a placebo! That concept makes sense,
and is quite believable, isn't it.

What can't be explained away scientifically or biologically, is that
homeopathic compounds work quite well when used to resolve
an animal's health problem! What does an animal know about
psychosomatic conditions? How can the compounds resolve
an animal's health problem, when a "placebo" is tried and does
not work, while the homeopathic compound does?

Homeopathic medicine continues to be used, and continues
to resolve many human health problems, and does so without
any "logical" explanation, and without being supported by any
scientific study.

MCP (modified citrus pectin), and/or any other alternative can
be denounced away by using any "scientific" means, just as
homeopathic medicine has been, but just who is being helped
by those doing the denouncing?

The first rule of the Hippocratic oath, is to: "Do No Harm".

How closely do modern-day physicians follow that important
rule, when they pump carcinogenic, toxic compounds into
an already sick body?

Does -that- make sense? Or should we only trust what can
be "proven with scientific study" and "clinical trials"?

I prefer Traditional Chinese Medicine (TCM), since it's been
used for four thousand years, and has served billions upon
billions of people for that entire time and continues to be used
successfully.

And like you, I never put too much faith into things that "don't
make sense" while serving the financial gain of some entity.

The herbs I had used, cost an average of $5 per pound. I used
eight different herbs, with one pound lasting at least one month,
while one pound of the herbs would last up to three months.

The cost of MCP is apparently an awful lot more than any
imported medicinal strenght herb I've used, but neither is "approved"
by our medical industry. That does not mean it doesn't work,
or can't be beneficial to someone taking it.

I dislike the "profit-grabbing" atmosphere surrounding MCP,
and have always been skeptical of such things that appear
to be dollar driven. Most people likely feel the same way,
yet trust the multi-trillion dollar cancer industry and their
chemical compounds that are promoted as "the only way"
to fight cancer.

There are many ways to better health, but choosing a route
that causes harm, simply does not make any sense, regardless
of any "study" otherwise.

Best of health to you!

John

janie1
Posts: 753
Joined: Apr 2011

Thanks to all who have weighed in. I appreciate both sides. While we all would love a magic bullet, we have to make our own decisions. Particularly I have to take into consideration (for my own take on this) the comments of Tina, and Lisa. Keep the research articles coming..... and for others sharing their experiences and knowledge. We do need to know as much as possible. One day things will be more clear-cut.
I, too, will look forward to questions to ask a naturopath. Just soaking in as much as possible. I'm sitting here with my to-go pump. Only on second time with Folfox-Avastin regimen for Stage4. I like to walk a lot to keep the circulation going. Not tired, appetite maybe a little too good. Thanks to all. janie

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3915
Joined: Nov 2010

If you like to walk alot , join the walking post.
hugs,
pete

Buckwirth's picture
Buckwirth
Posts: 1272
Joined: Jun 2010

You don't approve of citrus pectin, and I am cynical? Or are you saying that, because of the theory of homeopathy that no dosage matters?

I still don't understand. Honestly John, I feel like I'm being attacked for helping figure out the most beneficial dosage, based on a published trial.

What is that about?

Buckwirth's picture
Buckwirth
Posts: 1272
Joined: Jun 2010

John and I both know the difference between Homeopathy and Naturopathy.

Honestly, I have no idea what John is on about.

On the dosing, it is quoted in the study that "high-dose modified citrus pectin (1.6 mg/ml) on a daily basis"

1.6mg is the solid pectin to ml of liquid.

So each mouse is getting 1.6mg of solid pectin.

A mouse weighs 25 grams
150lbs is 68,0000 grams

The factor should be something like 2720

From there everything gets foggy. 2720ml is 92oz of liquid.

One thing for sure, I was not, and am not, making a judgement of the value of modified pectin. I sometimes like math problems, and the conversion is kind of a challenge.

Anyone want to check my math?

TxKayaker's picture
TxKayaker
Posts: 168
Joined: Jun 2009

I would think it is about 4.352 grams (solid) for a 150# man or 4,352 mg if your assumptions are correct.

Buckwirth's picture
Buckwirth
Posts: 1272
Joined: Jun 2010

So, my original math was wrong. (I blame insomnia and lack of the proper tools)

It is about 0.15oz per day for a human.

Thanks Tx!

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3915
Joined: Nov 2010

Hi John and Blake,

I hope you guys are enjoying your day. what an interesting discussions we all have.

I like the controversy, becuase it implies we are all still here discussung and well enough to type.

John thanks for rasing the "placebo effect" and the "do no harm" , reading this post raised my spirits. Again MCP is an alternative I have been trying and now had some studies behind it.

Yes modern science based medicine denies many the "placebo effect" , its acknowledged in clinical trials and is often almost as effective as the expensive modern drugs being developed.

1000's of drug trials have proved the placebo effect, why deny it to the masses.

In our quest for science based trials and answers don't rip let the faith and hope side of the placebo effect be lost. Just think about it.

In my hope and faith based approach to life and cancer treatment, my approach is leap first and ask questions later.

The answer to my survival is the "leap", the leap of faith is what I am refering to.

We are surviving as a community right now!!! this forum is immensley positive.

Real faith in our survival may unlock many bowel cancer patients immune systems.

I need to meditate more and give my scientific mind a rest and let my subconscious mind have a chance to do what it can. My brain is amazingly powerful and is not fully engaged in my recovery. I suspedt your brains are even more powerful.

just a different perspective, based on "the biology of belief" I have almost finished reading.

hugs,
pete

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