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Anybody have throat paralysis with Oxaliplatin

CarrieL
Posts: 13
Joined: Sep 2008

Just had my 3rd round of chemo Wed afternoon. Early Wed. evening I could not breath and had to call 911, chemo Dr. said I had a rare throat paralysis reaction to Oxaliplatin and now have to get allergy tested to see what my sensitivity is and next chemo treatment I have to stay overnight for monitoring. Anbody have this problem?
Carrie

lisa42's picture
lisa42
Posts: 3663
Joined: Jul 2008

Hi Carrie,

I had an allergy to Oxaliplatin, which was discovered the first time I had it during infusion. I got all itchy & broke out in hives & my lips got swollen. They stopped it, pumped me full of Benadryl & steroids, then proceeded very carefully. My subsequent infusions of it were stretched out over a much longer amount of time & they had me take some oral steroids and Benadryl at home before coming in each time, also.
I did have two times of being at home, however, and feeling like my throat was closing in when I was trying to swallow food. It was kind of scary. I never called 911, because it turned around fairly quickly. So, I don't know if they could give you steroids/Benadryl beforehand if they feel like the benefit of the Oxaliplatin is still worth giving to you.

I'm now on my second time of having chemo & my onc decided to not go the Oxy route again. (I'm taking Camptosar, Erbitux, & Avastin now).
Best wishes to you-
Lisa

CarrieL
Posts: 13
Joined: Sep 2008

I am getting allergy tested this coming week to see what my allergy is to Oxaliplatin, but it felt like I couldn't breath at all and was making funny sounds to get air into my lungs, very scary. How much longer did the stretched out infusion take? Right now I get it over 2 hours.

Marc141
Posts: 1
Joined: Aug 2008

I've had three rounds of chemo myself. They infused high-octane Benadryl before the Oxaliplatin. At the UC Davis Cancer Center they do that as a precaution for just about everybody.

msccolon's picture
msccolon
Posts: 1956
Joined: Oct 2004

I remember getting Benadryl by IV prior to by Oxaliplatin infusions as well. I did wind up having to drop it from the chemo after 3 treatments, though, due to nerve and muscle issues. Mary

angelsbaby's picture
angelsbaby
Posts: 1168
Joined: May 2008

MY HUSBAND WAS ON THAT HE HAD A HOOK LIKE FEELING IN HIS THROAT . COULD NOT DRINK ANYTHING COLD HOPE THAT HELPS

ANGELSBABY

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