Hi I am new . A stage 4 OC and with 548 CA125 level after first chemo cycle with carbo/taxol .
I am trying to find the highest levels known at the start of chemo .
can someone please give me some pointer .
Thanks a lot .
Welcome to the site,sorry we have to meet under these conditions. Please don't put alot of stock in the ca-125 #. it just means that your disease puts out alot of proteins that the test picks up on. I know of a girl with a ca-125 of 4050,and she was staged a 1c. For me my cancer doesn't put out alot of proteins, but I'm having a recurrence right now with a ca-125 of 54. It's a tricky little test to understand, but the numbers sometimes have very little to do with the volume of disease present. Good luck...and again welcome..(((hugz)))...Joanne
Welcome! I'm sorry you have the need to be here, but this is a great place to get answers and find support. My oncologist seemed concerned with my numbers not dropping much after the first chemo, but after the second treatment there was a BIG change. I asked him some questions based on my initial numbers, and he ended up telling me that he has seen them go above 5,000. But, like Joanne said, these numbers are just a guesstimate at best. They do NOT necessarily reflect the amount of cancer remaining. Try not to worry too much! Just focus on getting through treatment for now!
Welcome to this site. It has helped me in everyway. I am Stage IV also, diagnosed March 2, 2007. I had 3 liver tumors which put me in the 4th stage. Am considered tumor free and in remission now after 8 chemos, debulking surgery and radio freq. ablation of the liver tumors. I started with a CA-125 of 2988 and am now at a 5 but my oncologist thinks it is a good indicator for my cancer cells, but not everyone's. E mail me if you have any questions. Saundra
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I am Stage IIIc, I was 1632 at the time of surgery and as of 2 weeks ago was 6.9
Your CA 125 is your "marker" -you watch it go down with each treatment cycle and the norms are from 0-35 or 0-21,depending on what your doctor uses.
Best of luck with your treatments and keep posting. You'll get a lot of support here. Take care.
My daughter has 3c ovarian cancer and started out with almost 6000 CA 125 count. After two rounds of chemo, her CA 125 showed 167.
My CA125 was 9824 at diagnosis and is currently 12 4 months after chemo.
Love the news!
I was and am still stage 4 OC diagnosed 4/09. My CA125 was 2300 and now at 1150 after 3 different chemos. I'm getting ready to finish Topotekan and will be going to Gemcarz (sp)Hanging in there. Don't rely much on the CA125 stick to the cat scan
I think it must be a good marker for me. Before surgery, it was 4,000 and my nadir, about 60 days after I finished the Carbo/Taxol regimen, was 3.8
It has stayed pretty stable for the last 3 months, just below 7. But I am still getting Taxol (monthly) as maintenance, so that may be keeping the CA125 down.
I am still getting monthly blood draws but after I finish the maintenance, my doctor's protocol is every 3 months. I am going to ask him to leave me on monthly checks, and maybe he will compromise at every 60 days.
I am the other way round. My CT scan showed little change from when I finished treatment and my CA125 was 34 at it's lowest. But now my Current CA125 is 1,280.
This is a mystery. I am reading how many of you had very high CA125 at dx. I was dx with stage 3C. My ca125 was 111 (yes I have checked and rechecked the reports) Since chemo which finished last Nov I am holding at 5.2. It drops a bit with each 3 month draw. Anyone have any insight on this? I was told it would go up and down a bit even when NED.
Some of these numbers I am seeing are staggering. I keep dreaming that my initial count was because I did not have stage 3. Some dream huh? There are days I just want to throw the signals, etc out the window.
Unfortunately, the CA125 count has nothing to do with staging. Or maybe I should say fortunately, since mine was 4,000.
The CA125 is your body's response to an enzyme produced by the Cancer. Some people react very strongly and some don't. Also, infections, bowel obstructions, etc can cause a jump in the numbers.
Mine has bounced, roughly, between 4 and 7 for the last 7 months.
I was interested to read your views on CA125. Not sure if you've read any of my posts but my recent CA 125 has jumped from 71 to 1,280 in 2 months. However my CT scan looks relatively unchanged??? I am having bloating which I now realise is wind as my bowle movements are more frequent and smaller amounts are passed. My onc was unable to tell me exactly why the jump was so high yet the scan did not match and has put me on Caelyx (which I beleive is Doxil)
Do you think I may have a partial bowel obstruction? I am going mad here - it is very difficult to get hold of my onc as they are so busy. If so would that resolve itself once chemo starts? I know I should speak to my onc but I left a message last week and still not heard anything.
Thanks Tina x
Tina....a total bowel obstruction (and I speak from experience here) is very painful; you would definitely know if you had one.
I really think a BO would have shown up on your CT. Mine was diagnosed via a plain old xray.
Will your doctors consider doing a PET scan? They might get something to light up on a PET scan that the CT scan is just not seeing.
I think your doctor has done the right thing by puttin