CSN Login
Members Online: 26

Why cetuximab may not work while vectibix will:biomarker S492R mutation in EGFR

coloCan
Posts: 1845
Joined: Oct 2009

www.digitaljournal.com/pr/1530586

and an item on another nano approach to CRC

http://phys.org/print301131024.html

 

while a US-Russian collaboration is developing something called entolimod,CBLB502(some might also  want to delve into OncoVax or TAS-102 or U3-1565 or labetuzumab)

 

herdizziness's picture
herdizziness
Posts: 3397
Joined: Apr 2010

Why after tumor testing my onc switched me to Vectibix, now I wonder no more.  

Thanks hon,

Winter Marir

coloCan
Posts: 1845
Joined: Oct 2009

ago researchers suggesting switching from one to the other if the first stops working. Also, tho you might be predominantly KRAS wild at start of Tx,KRAS mutatant might become more prominant as therapy continues.As hard as we fight to kill cancer, the cells themselves are fighting to survive...We have to be stronger

 

(also,overexpression of a gene known as MET (there it is,an inch to the left of your screen)can also ultimately stop cetuximab from being effective; i'm sure there are other causes as well-there seems to be so many variables and every other day someone publishes research on another gene,protein,molecule that may or may not inhibit,nourish or do something else in CRC)

herdizziness's picture
herdizziness
Posts: 3397
Joined: Apr 2010

I'd been off chemo for 5 months and he had a lot of testing done on this last tumor, the cetuximab was only used for three months and worked very well in conjunction with the Irinotican, when I stopped getting it because of upcoming surgeries, but after looking a tumor test results before starting chemo again after this long lovely break from it, he said he was changing to Vetixmab (or however it's spelled, I forgot again).  I'll have to ask my onc why I guess.

Winter Marie

Scubadan (not verified)

I haven't been on for a week or so, and if you might have seen one of my last posts back then the cetuximab worked amazing for the 1st 3 mos, but things went crazy the 2nd 3 mos  with all kinds of new small lesions and new ones on my pancreas, peritoneum, and omentum fat. My onc has run out of options for me and did the genome testing. There is only one phase 1 study going on over in Dallas that he is trying to get me into. I'll ask him to read up on vectibix to see if that that is a better option for me.  Thanks for being diligent and informativee.

Dan

Subscribe with RSS
About Cancer Society

The content on this site is for informational purposes only. It is not a substitute for professional medical advice. Do not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Use of this online service is subject to the disclaimer and the terms and conditions.

Copyright 2000-2014 © Cancer Survivors Network