Oct 03, 2013 - 11:41 pm
My apologies for the long post. I am hoping that some of you can help me understand what happened to my mom or at least shed some light.
My 67-year-old mother passed away unexpecedly after only 5 months of being diagnosed with colorectal cancer with metastasis to the liver and 3 months of chemo (FOLFOX+Eribitux). She has undergone a successful total colectomy and was responding well to chemo. While no autopsy was performed, the cause of death was reported as heart failure. She had no history of heart disease, showed no major adverse reaction to the chemo and was only sick for the last 4 days before her death.
I am trying to understand what could have gone wrong. Could it be a reaction to the chemo? Is this expected given her condition? Any insight is highly appreciated.
Here is the history:
- Until Mid April 2013:
- Occassional constipation - Nothing out of the ordinary.
- Good general health. No illnesses apart from high blood pressure
- Late April 2013:
- Admitted to the hospital with total blockage
- Diagnosed with colon cancer (T 3 N 1a M 1) with metastasis to the liver.
- Surgery: Total colectomy (90% of colon removed) - no colectomy bag required
- Pathology report: Free surgical margins (nearest margin 5 cm) and only 1 out of 10 positive Lymph node metastasis.
- CT scan: 3 hepatic focal lesions of variable sizes affecting different hepatic segments - largest 7.3x6.8 cm
- May 12th, 2013:
- Discharged from hospital in stable condition (13 days post surgery)
- May 20th, 2013:
- CEA: H 3.4 and CA 19-9: 19.7
- June 22nd, 2013:
- CT scan: Progressive course of the hepatic metastatic deposits: Largest in the left liver lobe (segment 4b) about 7.5x7.5 cm. Newly developed lesions in the right lobe
- Late June-Sept 2013:
- FOLFOX chemo bi-weekly with Eributex adminstered weekly. Only missed 1 dose due to low red blood cell counts
- Aug 29th, 2013:
- CT scan: Relative regression in size of focal hepatic lesions seen in both hepatic lobes. Left lobe lesion measuring 4x4cm compared to 7.5x7.5 cm in previous CT scan. Small tiny nodule related to the right basal posterior aspect of the lung.
- CEA: 1.6 and CA 19-9: 13.4
- Sept 7th, 2013:
- Eributex adminstered (no FOLFOX dosage according to the schedule)
- High spirits, feeling better than she has ever felt since the beginning of chemo, back to driving her car, contemplating going for a beach vacation for a couple of days
- Sept 10-13, 2013:
- Fainted - low blood pressure, low heart beat, shortness of breath
- Condition progressively getting worse, skin turning yellow but refusing to go to hospital claiming that it is nothing too serious
- Sept 14th, 2013:
- Rushed to the hospital but unfortunately too late
Please let me know what you think or if have any questions about her diagnosis/treatment.
Thanks in advance,