CSN Login
Members Online: 10

Doxil and Prozac

Posts: 3
Joined: Aug 2011

Hi All

My wife is 6 years since first diagnosis of OVCA stage 3c. She has just finished Gemzar+Carbo+Avastin (3rd chemo course) with continueation of Avastin for 3 more cycles and the CA-125 has been clibing for the last 2 month to 600. So the Docs have decided to start her on Doxil. I have found out from previous posts that some patients used Doxil + Prozac since a study showed that Prozac increases the effectiveness of the Doxil. Has anyone been taking Doxil+Prozac. All the posts about this are from 2010 and I was wondoring if it was discountinued for some reason? Does anyone has information on this?



Alexandra's picture
Posts: 1310
Joined: Jul 2012

Hello Barry. I have no personal experience with either drug. Hopefully someone who does will pitch in.

I did the same google search you probably did and found no new information proving or disproving original 2008 article in Jerusalem Post http://www.jpost.com/Health-and-Sci-Tech/Health/TAU-study-Prozac-can-help-fight-cancer. I don't believe this combo is an accepted mainstream treatment.

There were anecdotal testimonials from a couple of patients in 2010-2011: http://www.inspire.com/groups/ovarian-cancer-national-alliance/discussion/doxil-works-better-with/http://www.inspire.com/groups/ovarian-cancer-national-alliance/discussion/feed-back-on-doxil/?page=7; http://csn.cancer.org/node/187874

Doxil (doxorubicin liposomal) and Prozac (fluoxetine) don't have interactions. If your wife has depression (and what OVCA patient doesn't?) I don't see how adding Prozac to Doxil can hurt her.

Best wishes,


Subscribe with RSS
About Cancer Society

The content on this site is for informational purposes only. It is not a substitute for professional medical advice. Do not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Use of this online service is subject to the disclaimer and the terms and conditions.

Copyright 2000-2015 © Cancer Survivors Network