Aug 13, 2013 - 10:31 am
I am looking for any advice concerning Casodex and MK2206 trial. I had RP in 2004 at Ford Hospital using the robotic DaVinci. My PSA had went from 0.9 to 5.6 from March, 98 to June, 04. In May, 03 it was 3.6 but I guess my Urologist was using the <4 rule so nothing was recommended. After biopsy with Gleason of 7, I elected RP in Nov., 04. Surgery went OK, but the doctor explained that he had to shave up the bladder neck margin?
My PSA stayed <0.1 until Nov. 07, I was told 0.1. Then 0.16( Feb. 08), 0.14(Jul. 08), 0.28(Feb. 09), 0.3(Aug. 09), 0.32(Oct. 09).
In Oct., 09, I elected (ON MY OWN) to go for radiation of the prostate area, total of 37 sessions.
My PSA values afterwards were: <0.1 (Apr.10), <0.05 (Nov.10), 0.05 (May.11), 0.15 (Nov.11), 0.15 (Jan.12), 0.22 (Apr. 12), 0.28 (Jun. 12), 0.32 (Aug. 12), 0.42 (Dec. 12), 0.59 (Feb. 13), 0.71 (May. 13) and NOW, 1.12. I am told that the PSAV is 5 months!
I would like some discussion as to what are my best options at this point. I am 69 years old.
Should I go into a Casodex and MRK2206 phase II trial knowing that I might be placed in the Casodex only group? Since the trial is 72 weeks, does anyone have experienced with Casodex only treatment? Without drugs like Lupron?
Should I forgo the trial opportunity and go for intermittent hormone therapy? If so, when should I start? Now, I would think?