Aug 10, 2013 - 8:49 pm
A little background info:
My very active, still working 85 year old mother was diagnosed with stage 3b colon cancer 11/2011.
She had surgery which revealed the tumor had penetrated the colon and she had (I think) 6 of 26 positive
Gene testing on my mom revealed her to have the gene mutation for Lynch Syndrome.
gene testing was done on the tumor as well but I don't remember the results right now.
She was then started on sodium phenylbutyrate (PB) 3/2011. She started on chemo but had progressively
severe allergic reaction to it (that the oncologist ignored) until she stopped breathing in his office. She had
about 4 chemo treatments... 3 really since the 4th infiltrated and went into the underlying tissues instead
of IV as it should have.
She just finished the PB one month ago.
3 weeks ago developed what appeared to be mild stroke like symptoms as well as an allergic reaction
to keflex.... went to ER, diagnosed with a stroke, 2 weeks later she had involuntary movements of her
lips as well as significantly slurred speech. Back to ER... CT scans revealed no change, no new "stroke",
ended up hospitalized and eventually an MRI was done which revealed a 1 cm lesion in the left brain in the
premotor cortex. CT of pelvis, abdomen and chest revealed no cancer. The "stroke" was they determined
seizure like activity from the swelling around the brain lesion.
Surgery 4 days ago revealed it to be adenocarcinoma metastasized from the colon.
further tests still pending. Mom's still in the hospital. MRI post surgery showed that they got the entire lesion.
No muscle weakness or paralysis as had been a concern, instead she is having trouble with slurred speech, trouble
swallowing and drooping left side of mouth (which has significantly resolved over last 3 days)
So far my homework has shown that colon cancer metastasizes to the brain only 1-2% of the time and usually
to the left. her's was on the right. Until tonight the only info I've found on treatment and survival has been dismal
at best. Tonight I found some that showed increased success with whole brain radiation... that sounds brutal.
Please point me in the right direction in finding what I need to help advise my mother on treatment options.
Thanks in advance.