Jun 06, 2013 - 6:56 am
Steve and I went to Montreal yesterday to find out what is next for him in terms of treatment. Up until this point we have believed the cancer to be in the liver only. Hoping for a two stage resection. If not, TACE, Theraspheres or any number of interventional procedures would have pleased us. Apparently there are now spots on the lung. This is preventing them from doing surgery. He's had a total of 27 Folfiri. Clearly, it is no longer cutting it. This surgeon is sending us to a new oncologist in Montreal. The regular onc is in Ottawa. The new chemo will be Folfirinox - oxaliplatin, irenotecan, flourouacil and leucovorin. Doesn't that sound like fun! They want to hit it hard and get the tumors under control and then do a liver resection, "with a curative intent.". To me, to even mention the c word is crazy, bit I do like their attitude. In addition, they are doing a biopsy of the liver. A piece of the tumor will be injected into a mouse. Steve will have his own mouse which will carry his tumor. Lucky mouse. They will do in depth testing to determine which chemos are effective on this tumor. Ottawa has tested for the KRAS mutation, which he has. They want to test for BRAF, as well. They will resets for KRAS. Apparently the fact that the primary tumor had the mutation doesn't necessarily mean the metastasis will.
I noticed on his blood work that the calcium level is slightly elevated. This has me wondering if there is bone involvement. He has no symptoms of it. No one has brought it up, but it concerns me.
All in all, it was very disappointing. I always go into these appointments prepared for the worse. Steve is a very positive thinker. Always thinks everything will just work out. He is very disappointed. Expected to hear lots of shrinkage, let's operate.
Thanks for "listening".