Mar 04, 2013 - 8:49 pm
I am new to this forum and would very much appreciate your take on my dilemma. My husband of 20 years, now 65 years old, whom I love from the depth of my being, has just gone through 6 cycles of CHOP chemotherapy and we're waiting for the result of the PET scan he had last Thursday. He has been, save for AITL, in good overall health (save for hemochromatosis that is kept under control), has handled CHOP with remarkable strength and relative ease after having been diagnosed on October 1st, 2012 with stage 3 AITL. Our own hematology team has suggested an immediate autologous stem-cell transplant/high-dose chemotherapy following the hoped-for full remission, starting this month, but another very highly esteemed t-cell expert in the field whom we just saw in a large Canadian centre has just told us that this procedure as a first-line therapy is not proven to have any advantages over merely CHOP for AITL patients and therefore they do not consider stem-cell transplant until after complete remission following a relapse. Plus he added that they would not even consider it in my husband's case as he has just turned 65.
I would very much appreciate if you could kindly refer me to any recent knowledge that might help in this decision. I had already searched and found several articles related to AITL and autologous stem-cell transplant performed several years ago with relatively good results but I could not establish if these results were achieved after the transplant being upfront or after relapse.
I have been in touch with a very kind lady through the buddy system earlier whose father, older than my husband and who had been diagnosed last year with stage 4 type B AITL, went through 8 CHOPS, had full remission and so far has been doing great, thankfully...
Thank you so very much for your kind help in advance,