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Testosterone rise rate after stopping HT (Firmagon)

dw055
Posts: 10
Joined: Dec 2012

I had temporary ADT during IMRT Radiation, 3 months. Anyone know how long it takes for Testosterone level to go back up. Cant find anything on this here or on the web. Even Firmagon company (Ferring Pharma) cant tell me. I know its different with each person, but some ball park idea would be helpful. I've had enough of no libido, impotence, insomnia and hot flashes..

VascodaGama's picture
VascodaGama
Posts: 1256
Joined: Nov 2010

Dw055

There is no timetable for rising testosterone. The worst effect after a hormonal course is if our brain does not start signalling to the testicles to manufacture androgens. Though rare, one should think on the probability for such to happen.

I have risen this subject in another forum and got some replies all indicative that the average time to start “feeling good” again varied between two and twelve months. This relates to the period with a starting mark at the end of the effectiveness of any agonist (leuprolide, goserelin, triptorelin, etc.) or antagonist (Degarelix). It seems that the longer the drug’s half-life the quicker one starts feeling a relief from the hypogonadism symptoms.

The return to normal levels of testosterone is also dependent on the length one has been in a hypogonadism status.
The “feeling good” and hypogonadism are differ among patients but one starts gradually to feel relief while still on castration in terms on levels of testosterone.

In my case on intermittent hormonal administration with just mono-blockade of 3 times 6-month shots Eligard (total of 18 months of effectiveness), I start feeling good two months after the end of effectiveness of the drug. At that time the testosterone level had risen a fraction from <0.01 to 0.11 ng/ml (11 ng/ dl) which classified me still on castration (normal levels are above 2.5 (250 ng/dl).
Libido was back ful