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manwithnoname
Posts: 393
Joined: Jun 2012

Might help some folks here.

http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst_detail_view&confID=114&abstractID=100408

 Paradoxically, none surgical CR patients (n= 16) enjoyed 100% 5-year relapse free survival compared to 42% of surgical patients "

 

manwithnoname
Posts: 393
Joined: Jun 2012

 Too important I think...

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3915
Joined: Nov 2010

hugs,

Pete

ps its a part of the navy protocol

richls
Posts: 54
Joined: Nov 2012

Can someone spell it out in laymens terms? Are they saying it is better not to have surgery?  Or is only better with a certain kind of chemo that is combined with 5/fu. These studies are very confusing if your not a doctor. Information that you can't understand is pretty useless for an average guy like me. They should have a cancer treatments for dummies book, lol.

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3915
Joined: Nov 2010

i'll let tony translate. these tabs are pretty blue and white stripes, they must be good for me.

hugs,

Pete

richls
Posts: 54
Joined: Nov 2012

Is celebrex an over the counter drug?

manwithnoname
Posts: 393
Joined: Jun 2012

Print this paper and take it to your oncologist, then come back on here and tell us what they said.

FYI my son is on 400mg Celecoxib daily. It's not over the counter.

Lovekitties's picture
Lovekitties
Posts: 2942
Joined: Jan 2010

Here is a link to an article from 2011 regarding use:

http://www.reuters.com/article/2011/05/11/us-celebrex-cancer-idUSTRE74A5SB20110511

It seems to be fairly unbiased, giving the pros and cons.

Marie who loves kitties

manwithnoname
Posts: 393
Joined: Jun 2012

     I still believe CSCs are more of a threat. Not advocating long term drug use, Celecoxib is/was used in a protocol.

 

The study will use a unique combination drug therapy of Capecitabine (a chemotherapy drug) and Celecoxib (an FDA approved arthritis medication) to “wake up” and to “kill” colon cancer stem cells. The treatment works by activating cancer stem cells that hibernate during chemotherapy—a chief cause of treatment failure—so they can be destroyed. The proper sequence is necessary to consistently kill the dormant cells. The ADAPT concept was proposed by Drs. Lin and Linheng Li, a prominent stem cell biologist.

It is a very powerful drug combination with good preliminary results. Pilot studies have shown significantly increased survival rates compared with conventional therapy. Of 124 treated patients, 40% of those treated with this protocol achieved complete remission or near remission with a median survival of 93.7 months and only 1/3 of the patients had surgical removal of the metastasis. The average length of survival for stage IV colorectal cancer patients on conventional treatment is about 20-24 months and 46 months for complete responders.

 

LivinginNH's picture
LivinginNH
Posts: 1302
Joined: Apr 2010

:)

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