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Does CA-125 fluctuate durring Chemo?

ptharp
Posts: 189
Joined: Oct 2012

Hi All: I am presently in Chemo. I just started my thrid round today (each round being 3 weeks). After my first round my CA-125 was 5. I had the test at the usual spot, but this week there was no lab technician at my ususal spot and I had to get it done at a different lab. Both places send to Nordx Lab. This week, my CA125 was 12. Should I be concerned?? Did anyone else that went into remission after frontline treatment have Fluctuating CA-125. Even though the labs were Nordx I am not sure they were sent to the same Nordx lab.

Alexandra's picture
Alexandra
Posts: 348
Joined: Jul 2012

My CA-125 was all taken by the same lab and was going down with every chemo round:
1083 -> 519 -> 126 -> 29 -> 18 -> 9 -> 8 -> 7

However I read that CA125 levels can and do fluctuate and marker is not the only indicator of how chemo is working. Check out http://www.wcn.org/downloads/CA125levels.pdf

ptharp
Posts: 189
Joined: Oct 2012

Thank you for the good information. There is a guy that comes to these board, I think he may be in the medical field said in one of his old posts that If the test was a different manufacturer it could be a different number.

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Tethys41
Posts: 1016
Joined: Sep 2010