Aug 30, 2012 - 2:38 pm
Reposted and extended for discussion. The Avastin molecule attacks VEGF molecules. We attenuate VEGF by other means. So far my wife has not been forced off her immunochemo by her surgery or dental work. If she were to temporarily stop the UFT (oral 5FU derivative), she would still be doing cimetidine (anti-VEGF) and IV vitamin C (histamine neutralization where histamine levels mediate VEGF generation).
Basically as much of the LEF protocols plus IV vitamin C and MK-4 as she can safely get away with (lots, with some supplement suspensions). In fact for her last surgery, her cimetidine intake doubled for the day. Her IV vitamin C may double or triple to fight infections, cancer and rebuild tissue, after surgery or dental work. I partly rate our execution efficiency by how soon after an invasive procedure that she can get the IV vitamin C infusion. Realizing the metastatic biotype odds with CA19-9 serum values over 15-20, not doing cimetidine looks risky to dangerous to me although the CA19-9 cutoff for initial diagnosis of (pancreatic) cancer is typically 34 - 40, depending on lab.
* A number of Japanese researchers consider the CA19-9 and CSLEX1 pair, used in combination, a fully predictive biomarker for metastatic risk and long term cimetidine benefit.