Jun 03, 2012 - 6:49 pm
Has anyone out there been on this trial? Did you have good results?
I think there are only about five of you out there in the world that have been on this trial...
The trial involves intratumoral adoptive transfer of alloreactive CTL that are directed against patient HLA antigens present on brain tumor cells but not normal neuroglia. Patients undergo resection for recurrent glioma and then receive multiple infusions of alloreactive CTL through a reservoir/catheter system that is implanted at the time of surgical debulking.