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Votrient Side Effects

KJones1969
Posts: 158
Joined: Mar 2012

My husband started Votrient Saturday to treat Stage IV Clear Cell RCC and I wanted to see if anyone else has taken it. If so what side effects have you seen? Thanks

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Texas_wedge
Posts: 2807
Joined: Nov 2011

If you go to the thread entitled "pazopanib side effects" you'll find good info. from ivfour who has been on Votrient (pazopanib) for some time. You'll find the thread at

http://csn.cancer.org/node/232668

It would also be worth while going into the archive at KIDNEY-ONC for further information from those who've taken it. This should get you some info:

http://listserv.acor.org/SCRIPTS/WA-ACOR.EXE

I hope this helps.

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alice124
Posts: 881
Joined: Mar 2012

Hi K - Just wondering how the patient is tolerating the Votrient? John started the MDX1106 and Votrient this past Thursday (5/10).

KJones1969
Posts: 158
Joined: Mar 2012

We are on day 12 of taking Votrient and the only side effect so far is he seems a little more tired. He says he isn't but I can tell by what time he is getting out of bed and going to bed at night. He has not had any of the other side effects we have heard about. We are being optimistic and praying nothing else happens even though the pharmacist told us 14 days before we know side effects.

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alice124
Posts: 881
Joined: Mar 2012

Same on this end for the most part. But he was at hospital this morning and they told him to drink more fluids as he was dehydrated. That kind of surprised me as I bought him a Vitamix as an early Father's Day gift last week, and he's been making and drinking fruit smoothies. I thought he was taking in more fluid than usual.

Let's continue to compare notes and keep our fingers crossed.

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Texas_wedge
Posts: 2807
Joined: Nov 2011

Another good move you've made. I make myself smoothies on a daily basis and there's no doubt I ingest even more fruit than I did previously and also have a larger fluid intake, despite trying to substitute a glass of a smoothie for a mug of espresso several times each day! It's a great way of guaranteeing constantly getting plenty of anti-angiogenic fruits and vegetables.

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alice124
Posts: 881
Joined: Mar 2012

You and the other users of Vitamix on this Board deserve the credit for this move. I didn't know what a Vitamix was until I googled it after reading one group of postings on diet. I thought Vitamix was a vitamin mix. But I'm glad I got it as it seems to encourage John to eat more often and healthier. He is thoroughly enjoying it.

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Baaa-bs
Posts: 50
Joined: Jun 2013

I've had my Vitamix for a couple years now. LOVE IT! Nice way to throw in veggies into your day!

Bennette
Posts: 65
Joined: Mar 2012

Incase you are still wondering, my mother has been taking Votrient for 3 weeks now and seems to be doing fine on it. We only had one morning of nausea before we started her on anti-nausea meds and she has been fine since - but that was on day 2 of the Votrient, so I am not sure if it caused it or not. Also, they had her on other things for appetite before she started Votrient, because she stopped eating after her kidney surgery. So those things might cover up any appetite side effects. So far we have not had to increase her high BP meds, which was the doctor's biggest concern with Votrient, she is still taking the same dose and we check her BP a couple times a day to make sure it isn't skyrocketing.
Hope this helps.

Bennette

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Texas_wedge
Posts: 2807
Joined: Nov 2011

That's the sort of valuable feedback that these threads are so good for and I'm sure I speak for everyone in saying how delighted I am to hear how well your Mother is doing.

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alice124
Posts: 881
Joined: Mar 2012

Thank you Bennette for the feedback, and I'm glad your mom is having none of the ill effects that we all worry about. Your mom's experience on Votrient so far pretty much is identical to John's experience. Let's keep our fingers crossed for them both.

One thing I've learned from dealing with Cancer is I have for most of my life undervalued a good laugh. Given that they come less frequently these days, I'm learning to enjoy them while I can. So--since you mention appetite stimulants for your mom, let me share with you a story I recently experienced relating to John (my husband). Maybe they have two drugs in common.

About a month ago with John's weight decreasing and my concern increasing over it, I encouraged John to call his oncologist and ask about an appetite stimulant, which he did. The Dr. called in a prescription to a local pharmacy and John went to pick up quickly thereafter. Once there, the trouble started. They couldn't find prescription; then they didn't have the prescription; then they were going to order prescription; only to come back and say "yes they have it. But is in the refrigeration compartment." Needless to say he was a little ticked off at the long, avoidable wait.

Later that day, he called me from one of our favorite restaurants where he was joining a few friends for lunch. I answered the phone to his voice saying, "Al, there's something wrong. I think I'm having some kind of side effect from the appetite stimulant." I immediately asked if he had gotten the prescription warning/side effect page with the prescription. He said he hadn't as they were anxious to get him out of there due to all the confusion with the prescription.

So I asked him what the name of the prescription was and I quickly googled, a bit frantic as he told me he had gone completely blank, lost total track of conversation, trouble with speech, etc.

As my google screen brought results, I felt a bit of relief. The prescription name was Marinol. I told John, "you're stoned." Marinol is synthetic Marijuana.

I can laugh about it now since he recovered and immediately stopped taking it. Personally, I thought he should continue taking it, but he very much disliked the LOST sense of control.

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Texas_wedge
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Joined: Nov 2011

I know how you can persuade him Alice! That lost sense of control could be just the job if he finds himself (as most golfers do, at one time or another) paying the price for 'steering the ball'. I shall look out for this medicine - I'm sure my round this morning would have gone far better if I'd been stoned.

Bennette
Posts: 65
Joined: Mar 2012

Alice,

Yes, my they put my mom on Marinol, but she is on the lowest dose 2.5mg and only started with it once a day at bedtime and then 5 days later they told me to give it to her 3 times a day, but did not increase the individual dose, she is still on the lowest per capsule. It is a pain that it has to be refrigerated, but ever since she started taking it 3 times a day she has been eating GREAT. She eats a whole meal for breakfast, lunch and dinner; plus snacks in between and her weight has been stable for two weeks. She hasn't complained of feeling "high" or anything, but she was/is on steriods too - I think they actually help balance each other out. I have heard that some people on steriods can barely sleep a full hour at a time, she doesn't have that problem and she can sit and read a book for quite a while before being compelled to move around. So for her it worked great. I was so distressed before because I couldn't get her to eat more than a bite or two for each meal after her surgery and she lost over 20 lbs in 2 1/2 weeks. So for her I consider it a miracle drug, she is eating like a normal human being now!

If he still needs an appetite stimulant, maybe you should check into the dosage they were starting him off on, maybe it was too much for him? I am pretty inexperienced with this stuff, but learning fast!

Bennette

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alice124
Posts: 881
Joined: Mar 2012

This is one of many reasons this Board is so valuable. His reaction made me question Marinol's legitimacy, but your response absolutely confirms it does what it's supposed to do for most people. I'm going to go home now and check to see what dose he was on???

20 pounds in 2 1/2 weeks is a lot of weight to lose. You're doing such a great job with your mom; keep up the good work.
___________________________
P.S. Even though John's reaction to Marinol was NOT one he liked or continued, we've had a lot of laughs about his being stoned. You'd have to know him to appreciate his response. He is pretty straight laced (but incredibly funny), and to hear him talk about distorted visions and other oddities--AFTER THE FACT--is funny. My stepson called John during his reaction and then immediately called me to say his father was incoherent. That is so NOT John. But like I said, we have fun laughing about it now.

mrbill38
Posts: 2
Joined: May 2012

I have been on votrient for over one year (since Jan. 2011). This was after I had been on Nexavar for over one year. My side effects on votrient at first was nausea, exhaustion, diarea, and loss of apetite. After three months, the dosage was reduced by 50% and the test results were fantastic. My tomors had reduced by about 50% and at least one had disappeared.
The last twelve months has been tolorable and have seemed to ease in side effects to the point that this year I've felt like doing some of the odd jobs around the house that I had let go. I walk every morning with my two four legged buddies and enjoy watching my garden grow. I do a one-hour program at a local assisted living home three times each month. So I feel almost normal most days. Other days I feel lousy, like yesterday. My Drs. are pleased with the results of using votrient to treat my cancer. I was first diagnosed in 1997. My wife, a wonderful caregiver, just walked with me at our latest cancer survivor relay a week ago. I'm 74 and plan to be around a long time. Bill Stephens.

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alice124
Posts: 881
Joined: Mar 2012

Thank you Bill for providing feedback. Not only is the feedback valuable but I find the sequence of treatment very interesting. Who knows maybe with enough note comparing we can identify the most successful sequences.

May I ask your type of cancer and stage/grade?

Sorry our introductions come under such lousy circumstance, but let's make the best of a bad situation. Sounds like you have a strong support group in both the two legged and four legged categories. Wonderful!

mrbill38
Posts: 2
Joined: May 2012

Sorry I'm a little late posting. I don't check my updates often enough to stay up to date. I don't really know what stage of renal cancer I am. I just know that I was diagnosed in 1997 when because of other medical situation I was in hospital for observation and to get high blood pressure under control when it was discovered that I had a tumor on my right kidney and another on the adrenal gland. Both were removed along with gallbladder and one rib. Surgery got it all and I was cancer free or in remission for about five or six years until small tumors were found during a scan about 2004. The upper lobe of right lung was removed in 2005. Treatment with Nexavar began January 2009. The results were so good that my Dr. took me off any treatment for about 18 months until the tumors started growing again. I was placed on Votrient in January 2011 and the results have been good. I am on 400 mg. daily and the tumors are responding positively. The results of the first scan 90 days after beginning Votrient showed that the tumors had decreased in size by 50% and one had completely disappeared. The last scan this past March showed some of the tumors were falling apart (the Dr. uses completely different terminology to explain so I have to ask a lot of questions to understand) so I won't have another scan for six months while still taking medicine on a daily basis. I feel great most days and am truly thankful that I am able to enjoy living. I entertain a group of seniors at a local retirement facility three Tuesday evenings every month and have been for nineteen years. I must give credit not only to the Dr. and staff that have been caring for me, the medicine, the technology, my precious caregiver for almost 55 years but I must give acknowledgement to my creator for His keeping watch over all the procedings. I must honor Him. Thanks. Bill Stephens.

KJones1969
Posts: 158
Joined: Mar 2012

Sounds like you have had some good results from Votrient. We have 2 months before they will do the first scan to see how Votrient is working for my husband. As I said the only side effect really he has had is being extremely tired and he said if that is the only thing that happens he can handle that. He is on 800mg a day so we will see how he does.

Thank you ALL for sharing with us.

KJones1969
Posts: 158
Joined: Mar 2012

Sounds like you have had some good results from Votrient. We have 2 months before they will do the first scan to see how Votrient is working for my husband. As I said the only side effect really he has had is being extremely tired and he said if that is the only thing that happens he can handle that. He is on 800mg a day so we will see how he does.

Thank you ALL for sharing with us.

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alice124
Posts: 881
Joined: Mar 2012

Bill - Your responses to the various treatments make your Doctor look like a genius. Whatever he tries, it works. The PERFECT PATIENT!

I am so glad you're responding again well and you can share that info with those of us and our loved ones who are just being introduced to Votrient. I also know about the language barrier in the CANCER world. It is like learning a new language.

It sounds like some of your successes may not only be to the terrific support you receive (Dr., wife, and God) but also to good Karma, 19 years entertaining seniors.

Good luck as you continue your fight. John will receive his first catscan since starting MDX/Votrient in three weeks, and I'll be anxious to compare notes.

montana4ever
Posts: 1
Joined: Oct 2014

Hi Bill,

I hope you receive this message, as it has been along time since you posted it. My husband (54 yo)has a rare form of Kidney Cancer and up until 1 yr ago there was no treatment for it. It does not respond to radiation or chemo. But they tried him on Sutent for this past year but it did not shrink his lympnodes.  They are now trying him on Votrient. He has only been on it for 1 wk and so far no SE except for some fatigue.  I was wondering what kind of cancer tumors you had/have that this medication was so successful treating.

Thank you in advance,

Sheelah

 

Well, I guess I should have read the next couple of posts. Now I know the answer, thanks anyway.

 

 

Bennette
Posts: 65
Joined: Mar 2012

We had plenty of fun joking about it too. You have to find something in all these meds, treatments, etc to laugh about or it gets way to serious all the time. I didn't think about this before, but pain meds make my mom goofy and confused. Since she is taking them for her spine mets, we probably won't have noticed any additional confusion! We already know she is thinking straight all the time! But sometimes, with everything happening so fast, I think it is better for her to be a little out of it - we take care of all the thinking for her until we can get into a better state and off some of the meds.

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alice124
Posts: 881
Joined: Mar 2012

Just wanted to let you know I did check John's dosage of the Marinol and it's .5. I read him your note about your mom's usage, and I think he may give it a second try at the lower dosage. It's good to compare notes.

Texas_wedge's picture
Texas_wedge
Posts: 2807
Joined: Nov 2011

It sure is - a spliffing idea Alice! :)
Er, maybe I should have said spiffing.
Seriously, I'm sure you'll have noticed some very valuable note-comparing going on on the listserv.

Bennette
Posts: 65
Joined: Mar 2012

Hopefully it will help him out.

I am not a big drug proponent, so I pretty much always ask for the lowest dosage of things to see how that goes before increasing it. I also think the lower dose multiple times during the day helps spread it out. But she started eating much better after they switched her to 3 times a day and that has continued to keep her eating well daily!

I hope it works for him too! I can't tell you how much stress went away when she started eating! I was more fearful of losing her to "wasting away" then I was of the cancer at that point.

Best Wishes!

KJones1969
Posts: 158
Joined: Mar 2012

Thank you for all of the feedback on the side effects or lack thereof of Votrient. My husband is at day 24 and his blood pressure is as close to normal or better than before he started it. Now they did up his bp medicine a few weeks earlier since Votrient usually makes it go up. The only side effect still so far has been tiredness. We were told it could turn his hair white, well it is getting grayer/whiter than before but not sure if it is the Votrient, age or me asking him all of the time if he is okay.

We go back to Duke Friday for a 4 week check up with blood work and to see Dr. Harrison. Last visit his protein was high so hopefully it has gone down some. If this appointment is good we will start going every 4 weeks with the first scans since Votrient at 3 months so praying for great results.

He has a great will power and will to live so praying this helps him.

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alice124
Posts: 881
Joined: Mar 2012

Hope Friday goes well for you and your husband. And I'm glad nasty side effects have been kept at bay so far.

To be honest, John continues to be on the weak side and gets tired easily. We go out but we usually don't stay out beyond a couple hours. I can't really blame it on the Votrient though, as he has not gained his strength since beginning the IL-2 treatment in January.

Of course, the pain in his shoulder continues and his overall weight loss I believe contributes to his lack of strength, but today--for the first time in several weeks--he said the pain wasn't as bad (as he almost forgot to take his pain medication). Perhaps a good sign. His weekly blood work this past week also was better than it's been.

You guys continue to be in my prayers. I'll be anxious to hear about your check up visit on Friday.

KJones1969
Posts: 158
Joined: Mar 2012

Yall are in our prayers also Alice. Friday will be 4 weeks of taking it so we will see how his appt goes. They will do a scan at 3 months to see if the Votrient is helping any. I ask his doctor about IL-2 before we started Votrient and he told me my husband wasn't a candidate for it. No pain meds is a good sign, my husband didn't take any 2 days this week so I hope that is a positive thing as well.

I'll update this weekend. Thanks for your prayers.

KJones1969
Posts: 158
Joined: Mar 2012

Yall are in our prayers also Alice. Friday will be 4 weeks of taking it so we will see how his appt goes. They will do a scan at 3 months to see if the Votrient is helping any. I ask his doctor about IL-2 before we started Votrient and he told me my husband wasn't a candidate for it. No pain meds is a good sign, my husband didn't take any 2 days this week so I hope that is a positive thing as well.

I'll update this weekend. Thanks for your prayers.

banddinbc's picture
banddinbc
Posts: 13
Joined: Jan 2013

Hi Alice -- I am learning here,  can you explain what vitamix is    my husband Don has RCC and is 12 days past his radical laproscopic nephrectomy,  we are in line for another CT wed in preparation to start Sudent after our onc ap

t on thursday and wondered if this is something we should use or at least know about. thanks Bev

 

adobe
Posts: 72
Joined: Feb 2012

Happy to hear your husband is tolerating the Votrient. It is a very good drug and was my doctors first choice. When I first started taking it I had side effects. I came to this site and received info from Tex and Foxhnd about the drug, along with alot of encouragement. I was discouraged when I could not take it, and visiting this site daily helped me through. The worst side effect was a rash all over my body swelling in my face, and bad liver tests which were monitered weekly. The doctor stopped the drug, and I was scared about what to do next. Doc said. just a bump in the road. and started Nexavar - 4 pills a day - still too strong. Reduced the dose to two pills a day, and all is well. I have the hand and foot syndrome for which I use creames
First ct since Jan. after trying both drugs came back as stable. I am not discouraged anymore and have learned to keep trying until something works. Lots of encouragrment to you!

KJones1969
Posts: 158
Joined: Mar 2012

We had our 4 week check up on Friday. Hemoglobin was low due to Votrient making it where is red blood cells are making enough is what the doctor said. His calcium level was low creatnine was high. Still the only side effect that my husband notices is being tired. He will have his first scan in 2 months so praying it will show a decrease in the spots on his lungs.

Adobe how long did you take Votrient before having a rash?

I have really enjoyed the support on this site.

NurseRatchit
Posts: 4
Joined: May 2012

For my two-cents worth......My husband had tried just about every chemo drug available when the Oncologist told him that there were no options. I had read about Votrient in 2010 - so asked him to give it to my husband to try it. He was skeptical and told us not to expect much.........

Out of all of the drugs, with the exception of Sutent, it gave him 11 months and the tumors reduced in size more than they had with any other drug! His only side effects were fatigue, high blood pressure (controlled with meds) and white hair. We cut his hair short and he looked like a cool cover of an aging surfer magazine! (We live in California) - Friends and co-workers thought he bleached his hair! Eventually, the little terrorists in his body became immune to Votrient, so we are now trying Inlyta, but it gave him another year! Good luck and Godspeed....

KJones1969
Posts: 158
Joined: Mar 2012

NurseRatchit,

It sounds like your husband had good news for 11 months. We are one month in and just fatique and high blood pressure but the meds to control that. Today is the first day he stayed in bed till early afternoon. I think my husbands hair is turning more gray or white, he says just grayer. Just curious how long before your husband starting turning white.

The doctor told my husband best case it will shrink some of the 5 tumors in his lungs. He said most likely it will just stunt the growth and extend his life some. I'm praying that he can stay on it 11 months, the doctor said if he can tolerate it he will take it up to 11 months. I'm glad you found Votrient and it gave him another year. After researching all of the kidney cancer drugs Votrient seems like the one with the least amount of side effects.

Good luck to you guys as well!!!

alice124's picture
alice124
Posts: 881
Joined: Mar 2012

Hi again Kay,

Just wanted to touch base again on Votrient. John's most recent bloodwork (5/31) also showed low hemoglobin (9.9) but it was better than his previous reading (5/10)when it was 8.3. So it's headed in the right direction.

His blood pressure is good (147/76), though it is a little higher than it's been. His Dr. discontinued his blood pressure medication after removal of his kidney/tumor in 10/2011. Prior to the surgery, he was on high blood pressure medicine, but his blood pressure was much lower after the surgery thus his medication discontinued.

His creatine level also is normal after being high on 5/10. So maybe the next followup will improve some of your husband's numbers.

Just a fyi. John's Dr.--concerned about bone strength--started him on Exgeva (or Xgevea) shots once a month a few months back plus started him on calcium and vitamin d daily.

I know things are tough, but don't give up. I saw your note on copay info and was glad to read you had found some help there. I know how draining these costs can be, particularly when dealing with everything else. Know you and your husband continue to be in my thoughts and prayers.

KJones1969
Posts: 158
Joined: Mar 2012

It sounds like things are going in the right direction for your husband. After my husbands nephroectomy in March his hemoglobin worked itself back up to 13.4 finally but after 2 weeks and more bloodwork it was back down to 12.2, that is still good but said Votrient could cause it to keep going down, praying it stays what it is because when he went to Duke March 15th it was 7.9.

I hope things are going good for John now, that is good creatnine was normal. We go back the end of this month and as always praying and hoping for good results. I hope when yall go back again everything goes well.

adobe
Posts: 72
Joined: Feb 2012

My rash appeared in 5 days -and it was the first choice drug. If you are four weeks into the Votrient therapy tell your husband not to give up being tired=sometimes the situation of cancer
concerns make a person tired, whatever the reason, get up and fight the feeling! Based on the tests and side effects the
doctor feels he can continue Votrient - it has proven to have good results. Keep us posted!

adobe
Posts: 72
Joined: Feb 2012

My rash appeared in 5 days -and it was the first choice drug. If you are four weeks into the Votrient therapy tell your husband not to give up being tired=sometimes the situation of cancer
concerns make a person tired, whatever the reason, get up and fight the feeling! Based on the tests and side effects the
doctor feels he can continue Votrient - it has proven to have good results. Keep us posted!

KJones1969
Posts: 158
Joined: Mar 2012

Well since mine has been on it a month with no rash that makes me feel good. Oh he is never giving up, is a matter of fact we have someone coming today to help him clean his shop out and rearrange it. I say as long as he wants to do something let him do it. I will keep you updated, we go back end of this month so praying for good results. Thinking about you and praying things go well your way as well.

Dan3546
Posts: 2
Joined: Jun 2012

Hi all - thank you all for the good info. My Mom was diagnosed with the non clear cell RCC; the DR. ordered her Votrient, but medicare sent Dad a letter saying they would not cover it. I was wondering how everyone was paying for these pill type drugs. I was thinking if we could get a couple of weeks worth to see how see reacted to the drug? Thanks for any thoughts or info. The hospital is still working on approval for one of these drugs, preferably the Votrient.

Texas_wedge's picture
Texas_wedge
Posts: 2807
Joined: Nov 2011

Dan, sorry to hear of your Mom's situation and your dilemma. I'm not in a position to give any info but I think if you can tell us what sub-type of RCC your Mom has then some others here will be better able to make useful comment. Did the doctor give you evidence that Votrient would be a worth-while bet for your Mom's sub-type?

If you don't get enough help here, you might want to join ACOR's KIDNEY-ONC online mailing list which has many members who are technically very geared up and might be able to assist you. I hope you get the necessary help in a tricky situation.

KJones1969
Posts: 158
Joined: Mar 2012

Hello! My husband is on medicare and they are paying for it, so maybe you have to argue with them some. We got our drugs from a specialty pharmacy and they helped with finding funding for the part medicare don't pay. Cancer Care out of New York gave us a grant to help pay for it, also if that doesn't work out Glaxo Smithcline, the maker of the drug has copay assistance. Good luck to you! Votrient has worked well so far with my hubby as far as side effects.

Dan3546
Posts: 2
Joined: Jun 2012

Thanks all - I know that the hospital has full time staffing just to try and get some of these pill type treatments approved with the insurance company and Medicare. The Dr. thougt that votrient would be a little easier on Mom's system and more effective to start compared to Sutent. Did not look at any real evidence of that. Mom has the Non clear cell RCC, Krome (sp?) 4 subtype. She did try an IV Chemo (Temsirolimus) last Tues, thought that might have a chance of arresting the growth while waiting for approval for the Votrient. But she no sooner got hooked up to it when her heart stopped; she was ok after a couple of thumps on the chest, but Dr. says nothing else for a week while she rests and trys to gain a little bit of weight back. One of the nurses is checking out with the Pharm tech to see what it would cost if we pay for it ourselves, at least enough to see how Mom reacts to it. Thanks for all the info. Dan

Sorry - looking at some of Dad's paperwork. Diagnosis states: a chromophobe subtype of renal cell carcinoma (the eosinophilic variant)

Texas_wedge's picture
Texas_wedge
Posts: 2807
Joined: Nov 2011

Above are many messages about the side-effects of Votrient (which is the commercial name for the drug pazopanib). I hope you find this helpful.

Texas_wedge's picture
Texas_wedge
Posts: 2807
Joined: Nov 2011

It's becoming ever clearer that drugs affect different people very differently so the following remarks are merely generalisations.

Since the period when surgery was the only treatment for RCC, we've seen the emergence of treatments with immunomodulatory agents, notably the interferons and interleukins. In terms of complete cure, so far only surgery (still our main weapon) and HD IL2, with its success for only a small proportion of patients, have been notched up. In the post cytokine era, the first of the new agents used for RCC was sorafenib (Nexavar) which had a range of unpleasant side-effects. It's now given way to sunitinib (Sutent) as the default first line treatment and many patients seem to find the concomitant side-effects endurable for the benefits it offers.

We appear to be at another point of transition where sunitinib is about to yield pride of place to pazopanib (Votrient) as the preferred first line of adjuvant defence. These changes seem to come closer and closer together and with a welcome feature of ever-better side-effects. It's not difficult to foresee BMS-936558 (MDX_1106) soon becoming the front-runner, with even more acceptable side-effects for most patients.

A recent study has shown that doctors and patients alike for the most part prefer Votrient to Sutent. This is because it is much more tolerable, particularly in respect of fatigue and quality of life. The abstract for anyone interested can be found at;

http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst_detail_view&confID=114&abstractID=98799

foxhd's picture
foxhd
Posts: 2058
Joined: Oct 2011

Great job Tex. That is as clear a breakdown of our current drug therapy as I've read or heard at any time. You're the best.

Texas_wedge's picture
Texas_wedge
Posts: 2807
Joined: Nov 2011

0:) !

angec's picture
angec
Posts: 664
Joined: Mar 2012

Hello, just wondering how your dad is doing. This is the first i have seen of this thread and i bumped into it at just the right time. It seems my mom might try to start on Votrient but the doctor is not sure that her coverage will pay for it. She has medicaid/medicare. Does anyone know if they cover this in NY?

Thank you and hope all is better!

KJones1969
Posts: 158
Joined: Mar 2012

My husband was able to take Votrient for about 5.5 months before being taken off of it. His 3 month scans were great but 2.5 months later he had new nodules on the lungs and the original ones that had a reduction in size were larger.

bry4856's picture
bry4856
Posts: 14
Joined: Nov 2012

Waiting for approval to start Votrient. I have had five cancers started at age 15, 17 stayed free till age 58 rcc and at 66 and how at 69. Never had chemo or radition

Texas_wedge's picture
Texas_wedge
Posts: 2807
Joined: Nov 2011

Someone must be watching over you!! With your perfect attitude, I'm thinking you'll do well on Votrient and you'll make nothing of the side-effects. I'm two weeks into it and doing fine at a few months older than you. Hope it goes to plan and the treatment avoids the need for yet more operations.

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