Dec 29, 2011 - 8:38 am
I post on the ovarian cancer site, but a friend of mine (in his mid 70s) thinks I know a lot about ALL cancer, and of course I don't. He had his prostate removed 14 years ago. 7 years ago his PSA started rising, but somehow this was never flagged. (We live in Scotland, and the NHS isn't always on top of these things.) This year they finally noticed that his PSA was over 60, so they did scans. He has a very small spot on his coccyx and another tiny spot on his pelvic bone. He received a shot of Decapeptyl (supposed to get this every 3 months) that knocked his socks off. He felt awful for 2 weeks. For 28 days he is taking 3 100mg. tablets of Cyproterone Ace. He has been "invited" to participate in a clinical trial called STAMPEDE: Systemic Therapy in Advancing or Metastatic Prostate Cancer-Evaluation of Drug Efficacy. He could be put in one of 5 groups, all of which include hormone treatment. 1) Hormone Treatment Only 2) Hormone + Zoledronic Acid (Zometa) 3) Hormone+Docetaxel (Taxotere) plus steroids 4) Hormone + the 2 drugs previously mentioned 5) Hormone + Abiraterone (Zytiga).
My friend is highly anxious and sensitive, and he's rather frightened by the possible side effects and having to drive 25 miles to the hospital every week or perhaps more. (Gas is about $9 per gallon, plus the Highland winter storms can be rather vicious.) Of course he wants to live and doesn't know if he is passing up on something that would prolong his life. MY thought is that since it has been 14 years since surgery and he has only 2 teensy spots on his bones, the added treatment could be overkill. I've also heard somehow or somewhere that there is a new targeted treatment for prostate cancer that has few to no side effects that will be available within the year. Is that true? Any information or advice you can give me for my friend would be most sincerely appreciated.