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IS a 0.47 PSA result GOOD?

RADIATION HOPEFUL
Posts: 208
Joined: Dec 2010

Hello ALL & MERRY CHRISTMAS TO EVERYONE

I got my latest PSA blood check yesterday & it came back 0.47 which is the lowest reading I evere had. I was wondering if this is a good sign of potential cure? (Responses welcome)
THANKS To EVERYONE on this site for the fantastic replies & concerns during the past year.

Cordially

Rad Hopeful

VascodaGama's picture
VascodaGama
Posts: 1569
Joined: Nov 2010

This is wonderful to read about your 0.47. Again another decrease and another moment to celebrate.
Nobody can tell you that such means cure but surely it means that the treatment has nock the cancer down.
I wouldn’t be surprised for another post of yours reporting about another decrease. Keep them coming.

MERRY CHRISTMAS TO YOU too

VG

RADIATION HOPEFUL
Posts: 208
Joined: Dec 2010

V Gama

YOU were correct--just got my latest PSA result & it is now 0.043.
Didn't go down much but it went down again
THanks to you & kongo for your E-mails ---I truly appreciate them

RAD HOPEFUL

Kongo's picture
Kongo
Posts: 1167
Joined: Mar 2010

Rad, that's great news and a special Christmas present. Your PSA continues to drop and you can't ask for a better sign.

K

RADIATION HOPEFUL
Posts: 208
Joined: Dec 2010

THANK YOU Kongo & VGAMA

I can always count on both of you to send a reply--THANK YOU SO MUCH & AGAIN A VERY MERRY CHRISTMAS & HAPPY NEW YEAR

Rad Hopeful

VascodaGama's picture
VascodaGama
Posts: 1569
Joined: Nov 2010

RadHope

Has your PSA gonne down to 0.043 from 0.47?

Is it a type error?

If you wanted to mean 0.43, that may be indicating that you are reaching the typical plateau in your journey. In any case, the percentage of the decrease is considerable for one month test.

Congratulations.

VG

RADIATION HOPEFUL
Posts: 208
Joined: Dec 2010

VGAMA

I MUST have typed incorrectly---the latest PSA went down 4 tenths to 0.43.

This still makes me HAPPY--it's still going down

THANKS FOR THE REPLY & SORRY FOR THE TYPO.

RAD HOPEFUL

Kongo's picture
Kongo
Posts: 1167
Joined: Mar 2010

Rad Hopeful,

I'm glad your scores continue to trend lower. As you approach nadir the rate of decline tends to slow. It's tends to follow a curve similar to what a quadratic equation would produce so the slope of the curve gets smaller and smaller as you approach the low point. All good.

K

RADIATION HOPEFUL
Posts: 208
Joined: Dec 2010

THANK YOU KONGO

THANK YOU for the reply, it made me feel good knowing I may be reaching the low point. I wonder if it's possible to get to zero?

RAD HOPEFUL

Kongo's picture
Kongo
Posts: 1167
Joined: Mar 2010

I don't think you can reach absolute zero but depending on how you prefer to round your numbers you can get pretty close.

RADIATION HOPEFUL
Posts: 208
Joined: Dec 2010

KONGO

THANK YOU FOR THE REPLY. There is a article on the internet by professor Les Bradbury stating PSA levels decline slowly after radiotherapy & can take several years to reach nadir. In fact , the longer the time to reach nadir & the lower the value , the better the chances are of remaining disease free. Some PSA bounce during this time frame should not be taken as a sign of treatment failure. Radiation works by damaging the DNA molecule in a cell. They either die at mitosis or peter out after a few generations. THE cells with fatally damaged DNA still continue to produce PSA & this only ceases when they die. As a result -PSA declines quite slowly after radiotherapy. Clearly the lower the final nadir , the better the long term prospects are of remaining disease free. If the treatment has been successful, all the cancerous tissue will have been destroyed but healthy prostrate cells are more resistant to radiation dAMAGE & some of these will remain. The prostrate gland will be reduced in volume but will still produce residual PSA. BOTTOM LINE> the lower the final PSA nadir & the longer it takes to reach this value , the better the chances are of remaining disease free.
Thought you might be interested in this article--hope you don't mind I sent it. Actually it reflects what you stated in the reply---THANK YOU & BLESS everyone affected with this disease.

Cordially
RAD HOPEFUL

barry2468
Posts: 9
Joined: Jan 2012

Good luck to your future PSA levels. In my case I had 116 psa reading before I embarked on a treatment of Eligard (Oct 2010)after watching it for 11 years. It rose from 10 to 116 in a short 4 months. 2 months after the injection my reading dropped to 0.29 and after a further 2 months to 0.17. Good stuff. After a further 6 months it rose to 2.7 and after a further 2 months it went to 21.0. I had a further needle in Oct 2011 (a year apart) as I believe in intermittent medication as required. Today it is still 2.6. By choosing intermittent as the way to go is because I believe the less you use it the longer will it be effective. The norm is every 4 months so in the long term I am saving a hell of a lot of needles. My Urologist does not agree with me on the point but after reading up on it for the last 12 years I prefer to make my own decisions as the specialist doctors have made a hell of alot of mistakes in the past and will continue to do so. Barry

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