My husband had an RP in 1999. Gleason 8 found on biopsy. Cancer in one interior lobe, did not spread. Said on report that he had perineural invasion. Did not ask at that time, surgeon did not spare nerves as he said cancer "climbs" and majority of RP he has performed, cancer eventually returned. Five years later, his annual PSA was 2.57. I was shocked and unprepared. All doctors said "nothing to worry about for it had been 5 years." Well that was when I educated myself since it showed that majority of doctors knew very little about PC. The information I received was ridiculous.
It has now been three years and since that time, we do and "on" and "off" treatment, but the latest treatment has lasted for over a year after only ONE HORMONAL INJECTION, 50 mg casodex and Avodart to bring down the DHT (dihydrotestosterone) since his DHT was 30 and it is known that it is a much more powerful testosterone than regular T. Avodart immediately brought it down to 3! T is eventually increasing back to a normal range and the PSA has increased after 9 months of no meds to .013. Our urologist, specializing in PC, wants to begin HT if it reaches 0.2 and I am saying it is much too early. I would wait until at least 1, for the longer we are "off" the better off we are! Every doctor has a different angle or answer. So frustrating. Taking turmeric (curcumin) daily, POM, Calcium for bones, Vit. D, Reservatrol in hope of prolonging not going back on hormonal. We are know thinking, per another doctor's advice just to take 50 mg Casodex a few times a week and NOT take hormonal therapy injection, still staying on Avodart, to see if that would bring PSA back down to 0.01 which he has been since August 2010. Another thing, many doctors do not do the ultra sensitive PSA, Labcore and Quest have them, regular PSA only go as low as 0.1, whereas Post prostatectomy PSA's go to 0.01. Any many having an RC should not have his PSA higher than 0.10 for if higher shows cancer is recurring. He also had 33 radiation treatments in 2008,but did not seem to lower PSA at all! A doctor verbally time stamped him with a life line of 6 years, which I never forgot, for know I know he as full of baloney. Where is the cancer - in the prostate bed, did it metastisize, MRI in 2008 of chest and lymph nodes, showed nothing. Is it too small? Getting educated is your best way and also never listen to even one two or three doctors, unless you get all the information yourself. Some men wait if recurring PC PSA is 2, I do not know whether that is too high or not to re-begin hormonal therapy and/or casodex/avodart. The recent discussion on Avodart/Proscar bothered me until I began to understand the ambiguity of it all in reference to men WITH or recurring PC. Over 10 years ago doctors were not even REQUIRING PSA's. I always requested one. You would think since this is a men's disease they would have jumped on their own illness bandwagon decades ago.