Help requested

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Grietje
Grietje Member Posts: 2
in Lymphoma (Hodgkin and Non-Hodgkin) #1
Dear readers,

My name is Derk and I am from Holland. My brother now suffers cancer for 9 years. it has been 'banned'' and returned 4 times. He has had dozens of chemotreatments, radiations etc etc. From the treatment alone you can kill someone. Currently he is sort of 'given up here in Holland.
The only treatment that might help is SGN 35. I understood that is it not yet legal but in some locations one can get prescriptions in a form of trial.
Can anyone tell me how to obtain SGN 35, preferably abroad or in the US.
Otherwise please supply an address at which I can contact the producer.


Much obliged for any answer
Derk

Comments

  • JoanieP
    JoanieP Member Posts: 573
    #2
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    Sorry
    Hi Derk
    Sorry I have never heard of any drup like that. Tell him not to give up. There are so many different things an ONC can try. Good luck to him and keep the faith
  • CountryGal7557
    CountryGal7557 Member Posts: 164 Member
    #3
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    Mayo Clinic or MD Anderson
    Derk....I searched brentuximab vedotin (or SGN-35) at Mayoclinic.org and also MDanderson.org and found a couple references to a phase I and II study/trial. MD Anderson appeared to have more information to read. I'm sure there are other repritable clinics in the US, I have just heard of these two more than others, so thought I'd pass this on for your research. Good Luck and I hope you and your brother find some answers. Keep the faith and keep researching, asking, calling until you get answers. Janelle

    Mayo Clinic, Rochester Minnesota
    http://www.mayoclinic.org/cancer-treatment/clintrials.html


    MD Anderson Center, Texas

    http://www.mdanderson.org/publications/conquest/issues/2011-spring/also-in-the-news.html

    Armed antibody for Hodgkin’s lymphoma

    An antibody loaded with an anti-cancer agent — brentuximab vedotin (SGN-35) — produced complete or partial remissions in 38% of patients with relapsed or therapy-resistant Hodgkin’s lymphoma.

    “That level of objective responses to a drug is impressive for a Phase I trial,” says study lead author Anas Younes, M.D., professor in MD Anderson’s Department of Lymphoma/Myeloma.

    “There hasn’t been a new drug considered for Hodgkin’s lymphoma in 30 years. These encouraging results are being confirmed in a large Phase II trial.”

    Reported in the Nov. 4, 2010, edition of The New England Journal of Medicine.
  • Grietje
    Grietje Member Posts: 2
    #4
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    CountryGal7557 said:

    Mayo Clinic or MD Anderson
    Derk....I searched brentuximab vedotin (or SGN-35) at Mayoclinic.org and also MDanderson.org and found a couple references to a phase I and II study/trial. MD Anderson appeared to have more information to read. I'm sure there are other repritable clinics in the US, I have just heard of these two more than others, so thought I'd pass this on for your research. Good Luck and I hope you and your brother find some answers. Keep the faith and keep researching, asking, calling until you get answers. Janelle

    Mayo Clinic, Rochester Minnesota
    http://www.mayoclinic.org/cancer-treatment/clintrials.html


    MD Anderson Center, Texas

    http://www.mdanderson.org/publications/conquest/issues/2011-spring/also-in-the-news.html

    Armed antibody for Hodgkin’s lymphoma

    An antibody loaded with an anti-cancer agent — brentuximab vedotin (SGN-35) — produced complete or partial remissions in 38% of patients with relapsed or therapy-resistant Hodgkin’s lymphoma.

    “That level of objective responses to a drug is impressive for a Phase I trial,” says study lead author Anas Younes, M.D., professor in MD Anderson’s Department of Lymphoma/Myeloma.

    “There hasn’t been a new drug considered for Hodgkin’s lymphoma in 30 years. These encouraging results are being confirmed in a large Phase II trial.”

    Reported in the Nov. 4, 2010, edition of The New England Journal of Medicine.

    Thank you both for replying so swiftly, we do keep up the hope, however sometimes there is this dip. With this information I try to speed up the process of obtaining the cure.
  • michelleb1064
    michelleb1064 Member Posts: 53
    #5
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    SGN 35
    The drug is being studied at the University of Alabama at Birmingham. And is being manufactured through Seattle Genetics. I have included the web site for Seattle Genetics. If you click on the link a page will appear. At the bottom of the page reads currently enrolling clinical trials, click on it. It will hopefully guide you where you need to go.
    Good luck to you and your brother.

    www.seagen.com/product_pipeline_sgn35.shtml

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