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chromogranin A test



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flapjack
Posts: 4
Joined: Nov 2009
April 6, 2011 - 11:51am

Hi,
I am glad to find this site, very helpful. I am currently being worked up for pheo/carcinoid/neuroendocrine... Have classic symptoms. My chromogranin A came back elevated from Quest diagnostic:

Chromogranin A SERUM 26.0 (H) ng/mL 1.9-15.0 (normal range per lab)

What does this mean, does not seem very high, are there others out there and what were your levels? I don't find much on the internet as to how high this is in patients with different neuroendocrine tumors. Thank you

bbtaxman
Posts: 1
Joined: Apr 2011
April 6, 2011 - 4:58pm

I just read your comments and levels. My GI doctor said normal was 7 to 15. Yours is at 26. Mine came back at 58... YIPES. I've had an upper and lower GI done. They are now getting approval for them to give me a camera the size of a pill so that they can see my lower intestine. That should take place in a couple of days from now.

You are right. The information online is more clinical. I need it in plain English. Try looking up Chromogrannin A which is the hormone involved with all of this. Although the doctor said that 80% of the tumors are begnein I'm still concerned about the 20%. He also said that this was rare. Figures right?

Feel free to contact me if you want to talk more about it.

flapjack
Posts: 4
Joined: Nov 2009
April 6, 2011 - 5:43pm

Thanks for the reply, I too am lined up for endoscopy/colonoscopy next week and then the capsule test. The GI ordered the chromogranin and gastrin prior to these tests based on my symptoms and family history.

I don't think the 26 seems too high, but don't know what high would be. The 58 is definately higher but hopefully these are low enough to not matter. I have seen on some sites people as high as 3000, but I did not know the "units" they had used, or their normal range.

I hope my GI orders more blood/urine now that the chromogranin is slightly high, did you have other tests done?

Good luck and keep me posted I will when I find out anything.

klisesr
Posts: 15
Joined: Nov 2010
April 6, 2011 - 7:45pm

Hi - I was diagnosed in 2006 with ileal carcinoid (malignant with positive lymph nodes). My Chromagranin has never been considered "high" - but beware that the level considered as high differs depending on the lab where the test is run. My doctors who diagnosed me also said that most tumors are benign - mine was not. They then said I was "cured" when they removed my primary tumor and positive nodes - and I was not. I had surgery to remove numerous tumors from my liver 4 years after my initial diagnosis. I'm not trying to scare you, but please seek out the experts in determining your care. There are resources available to assist you with finding the right doctor (carcinoid.org or caringforcardinoid.com). I still am doing well and lead an active life at 42 years of age, but I have learned the value of seeing an expert through my own experiences. There is no "one size fits all" in medicine - each person is different, and needs a doctor who understands this.

jensor06
Posts: 1
Joined: Jan 2012
January 19, 2012 - 5:46pm

So, I just had the chromogranin A test done. They sent me my results and, while I know a high level is not a good sign, what does it mean when your level in below what is considered normal?
I called my doctor and they won't see me for a week.
My results said <1 and was in big, bold, red letters. If a low level is good, why mark it in bold red? None of my other results were marked in red.
Anyone have any idea? I tried called Quest and they just said to discuss it with my doctor.

Radioactive34's picture
Radioactive34
Posts: 355
Joined: May 2011
February 1, 2012 - 7:18am

What did your doctor say? Did they have other tests to use as a baseline? I am curious as this test was something that was going to be used for me or was used....but was always fantastical and mystical.