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TheraSpheres/Y=90

slg
Posts: 200
Joined: Jan 2010

Has anyone out there had this treatment for their Liver tumors? If so, how were the results? any side effects?

imjb73
Posts: 34
Joined: Jan 2011

My husband had one done a couple months ago and had another today. He has been extra tired. And had a bad taste in his mouth for a while. Things don't taste right and he has lost some of his appetite. They have done one scan since the first implant and said it looked smaller but it was really too soon to tell. He will be rescanned in about another six weeks and we will see what the results are. I wish I could be more help to you but it's too soon for us to know for sure what the outcome will be.

slg
Posts: 200
Joined: Jan 2010

Hi,

Thanks for your input. I hope this treatment works for your husband. Keep me posted. Where did he have it done?
We are still waiting to hear if the doctors want to proceed and do this treatment to get my husband back into criteria for transplant.
Is you husband needing a transplant?

Tina Blondek's picture
Tina Blondek
Posts: 1564
Joined: Nov 2009

Hello Slg
Yes, I know of a couple here whose husband had this treatment done. I am just having trouble remembering their names. Jim and Linda come to mind, but not sure. Jim and Sally maybe. Hope someone comes to our rescue! I will check back in a few days and see how you are making out with your search.
Tina in Va

imjb73
Posts: 34
Joined: Jan 2011

I thought I posted a reply yesterday but I don't see it. So I will reply again just in case. Indiana University Hospital is where he is going. He needs a transplant but the tumors are too large and too many. The Y90 is the treatment being used to try to shrink/kill the cancer enough for him to be qualify for a liver transplant.

dlaarndt
Posts: 6
Joined: Dec 2010

My husband had the Y90 to the right side of his liver after he could no longer get any further treatments because his count was too low. He then some how fell through the cracks and was suppose to have the other side done in four or five weeks. His first was 2-7-2011 then this past week he had a CT scan and found that the tumor had gotten larger - which they dont know if the spheres inflammed the tumor or it really grew, he also had spots on his lungs which got bigger. He starts chemo again this week. Has anyone had side affects like his..He has had cold systems since the spheres which he went to the doctor for. He was sick to his stomach since and takes pills daily. He also has had a low grade fever. I did do some research on the internet and they do say the liver can enlarge and the CEA can spike which his went from 224 to 842. Any information is greatly appreaciated..

slg
Posts: 200
Joined: Jan 2010

Well, can't say that's encouraging. I was hoping for more positive information. Hope your husband pulls through.

dandickinson33
Posts: 2
Joined: Jan 2011

Y90 is magic stuff. The web site of the manufacture is at:

http://www.nordion.com/

When I talked to the manufacture, they said the folks with the most experience were at Northwestern University in Chicago. I had the proceedure with zero side-effects. It was over a year ago and it killed the cancer. I outlined it all on my blog.

http://flyme33.wordpress.com/

Good luck...

slg
Posts: 200
Joined: Jan 2010

Hi Dan,
Wow, it is so encouraging to finally get some feedback and positive information. My husband and I would very much like to stay in contact and I need to know more. I am reading your Blog but have a lot of catching up to do.
So when were you diagnosed, 2009? And when did you have the treatment? and when was your transplant.
I assume all were done at Northwestern. We live in California but will be going to Kansas City to the University of Kansas Medical Center for the transplant. My husband has one too many tumors for criteria and was put on hold so we REALLY want this treatment to work so he can have his transplant in the next few months.
My email is slg72@aol.com. I will continue reading your blog and am sure my questions will be answered but it will take some time to catch up and thought maybe you could answer those few questions more quickly than my reading.
Thanks and congratulations on your second chance!!!
SLG

rwp1958
Posts: 2
Joined: Feb 2011

How did you get referred to the Y90 procedure?

I have portal hypertension of the liver and 2/3rd's of my liver has already been removed. I have 2 tumors left on my liver and no way to treat them due to extreme low platelets.

Thanks
Randy

Pennymac02's picture
Pennymac02
Posts: 336
Joined: Aug 2010

My husband had three bland embolizations. His liver was already too sick to handle any chemo by the time they started treatment. His HCC was very agressive, tho, so on the third embolization they were very agressive in cutting off the blood supply to the largest tumor in order that he's meet the criteria for transplant.

The treatment worked in that it stopped the cancer from spreading and growing, but the liver went into failure because they also stopped the blood flow to the small amount of healthy liver tissue he had left. After the last embolization at the end of October he was hospitalized numerous times, then in November he went into the hospital, was airlifted to Richmond for the VCU transplant center, and he made the list for only one week before he developed and infection and passed away on January 14th.

I don't remember anyone telling us that the treatment would send him into liver failure. They probably did, but I was in such a state of sleep deprivation and shock, that I didn't hear it. Either way, his only hope was to be able to get a transplant, and he passed while on the waiting list. Sorry to be the bearer of such doom and gloom.

slg
Posts: 200
Joined: Jan 2010

Update! Since my husband's CT scan almont one month ago we finally got approval for a Therasphere procedure to treat his new tumors.
It is beyond me as to why everything takes so long. We are grateful that we finally have a date for part 1.

imjb73
Posts: 34
Joined: Jan 2011

I'm glad you have a date for it.We were told it would be a fight to get insurance approval. It did happen though. Now they have denied to cover the pet scan. They said it wasn't needed. They just keep us jumping through hoops. I also wanted to let you know the 2nd treatment has really knocked my husband down this time. I'm not sure exactly how much is from the implant or just the disease itself. But he isn't bouncing back as well this time. Some of it like being tired is expected. He hasn't been eating much and having trouble keeping the bad taste out of his mouth.
Wishing you GOOD LUCK!!!

slg
Posts: 200
Joined: Jan 2010

Hi,
Would like to hear more about your husbands tumors and treatment. How many tumors did he have; when was he diagnosed?; is he on the transplant list yet?
We have been participating in a support group for transplant patients. They talked about the taste issues and said that salsa helps make food taste better. have your husband try that.
You can email me at slg72@aol.com.
Thanks for sharing your information.
SLG

slg
Posts: 200
Joined: Jan 2010

Today my husband had his regular appointment with his hepagologist. We got some encouraging information from him.
After next week's angiogram with the radiologist he could schedule the Therasphere procedure as soon as two weeks later. That is what we are hoping. With all the research I have done on this procedure it could be done in anywhere from 2-6 weeks! So if it happens in two weeks we will be very happy. We have to get through next week and make sure they can do the Therasphere procedure. His Doctor seems to think there should not be any reason they won't be able to.
Then the waiting will begin. The Dr. at CPMC is going to talk to the KUMED Doctor about the followup CT scan and see if it's really necessary to wait 3 months. We are hoping he will relax his decision on that and hoping Paul will be back to active on the transplant list soon after the CT scan.
This is our only hope that he gets the transplant!!!

kohsin
Posts: 27
Joined: Apr 2010

I am happy to say that my Y-90 treatment prior to my resection (9 cm) helped a lot. No obvious side effect, only 2 weeks after the treatment and the tumor reduced by 2cm. The surgery was as good as it can be. This was Feb 2010. Good stuff and good luck to all

ljg6991
Posts: 1
Joined: Jul 2011

I have secondary liver cancer which was diagnosed in Jan of 2011. I have had 2 theraspere treatments and 2 mappings prior to the Therasperes/ I was told that I wan not a candidate for a resection even though the first treatment was successful. The reason that I was given, was that my liver cancer is secondary and came from my ocular melanoma in my right eye and that I have cancer cells in other parts of my body. The lesions have only shown up in the liver as yet. Do you have primary or secondary liver cancer? And what is your prognosis? Thanks

slg
Posts: 200
Joined: Jan 2010

Thank you for your posting. My husband has primary liver cancer. Unfortunately when he had the Y-90 treatment there was one tumor that they couldn't get to because of the location. Now that tumor is preventing him from getting back on the trasnplant list. We are now heading out to Kansas for him to have a Dyna CT and Radiofrequency ablation in order to get to that one tumor. Then, hopefully, he will become in criteria and get on the list.
Best of luck to you and keep the faith. Don't give up!!!

imjb73
Posts: 34
Joined: Jan 2011

We got good news today. The treatment seems to be working. His cancer markers have dropped almost in half and what was lots of white on the scan is now small spots. He is anemic and his albumin level is low. Nutrition is being suggested. Eat healthy and add ensure, boost etc. This is the best news we could get at this point. Don't know yet if they will do a lung biopsy. He might qualify to get on the transplant list soon. This is a big improvement from him being in the hospital and non responsive a week and a half ago.
The doctor gave us hope today.

slg
Posts: 200
Joined: Jan 2010

So glad you got some good news. Good news is always good!!! We also have some. Yesterday was the first part of the two part Y-90 procedure for my husband. We are waiting to hear when the Y-90 procedure will be. Just found out this week that someone who had the Y-90 over a year ago finally got his liver transplant this week. He is our inspiration!!! We look forward to being there too, soon, we hope!!! and hope that you will be there soon too. It's always good when the lab numbers go down. Keep in touch!

imjb73
Posts: 34
Joined: Jan 2011

I don't know how often these treatments are done but my husband has had 2 so far. But when the doctor came in yesterday to talk with us we found out he had done 3 yesterday as well as seeing patients. I guess he had so much going on yesterday they had to reschedule some appointments. He is a busy man but in giving us our news yesterday he was like a different person. I guess that's good. I can't imagine having to tell people the worst of things so much. He is a tad arrogant. Says he's the best. I want the best so he can act how he wants to if he can help. The doctor I seemed to like the most through all this so far is the one that told us 2 different times there was no cancer. So bedside manner is important but only to a point. Happy for you that the first part is over. They usually do the second part within a couple weeks. Keep us posted.

slg
Posts: 200
Joined: Jan 2010

Y-90 was performed Wednesday and it appears all went well. So far the only side effect is tiredness but then he has been tired all along with the Nexavar. We are hoping that this does the trick and he will be back active on the list in 3 months and then we can get on that plane to Kansas.
Tha waiting is very hard but I think we have gotten pretty good at it.

lindaprocopio's picture
lindaprocopio
Posts: 2022
Joined: Oct 2008

Just wanted to post that I would strongly recommend anyone with cancer in their liver to at least explore radioembolism. I had the right side of my liver 'radioemboloized' June 1st. Yesterday I had preliminary blood labs and CT-scan liver study. The early feedback on my scan and labs was VERY encouraging.

The tumor progression marker for my type of cancer is CA125. My CA125 dropped by over HALF, comparing the labs taken just before the radioembolism to the labs I had yesterday. & although it is really too early to tell too much from a CT-scan, the radiation interventionist said that the right side of my liver is "improved" and the left side is stable. I will be getting the left side of my liver radioembolized in mid-August, as we are working around my vacation & the surgeon's.

isabella724
Posts: 1
Joined: Jul 2011

I was diagnosed with HCC on April 1, 2011. I had no symptoms, so the news was such a shock!!! I have had a complicated health history.....It seems things get more and more interesting! I wanted to share my experience of the effects of Y-90 Theraspheres, because I was not very prepared for what has happened. First, I would like to wish anyone who is able to have this procedure done to definitely find a way to do it!!! Secondly, I hope that the medical center AND the doctors that help you are very communicative, helpful, and available. I was left up in the air for 6 weeks after the first angiogram, in which they determined if I would be a candidate for the procedure. As you well know, waiting is so anguishing!!! The interventional radiology department 'lost' me while staff vacations and changes were made. I had been calling and calling. Finally, I was told that I WAS approved, but that because the doctor's schedule was full I could not have the first treatment until 6 more weeks. No one seemed concerned about the 8cm tumor that 6 weeks before all the medical people i'd seen practically had me planning my funeral!!!!!
What I most want to convey, is to make sure that you can get good information and have a team that is available and will talk with you and check in with you. I had EXTREME pain during the angiogram in which they did the 'mapping' and implanted the coils. I was admitted to a local hospital (my treatment center is 5 hours away) for pain management. The first implantation of the spheres went so much better.....absolutely NO nausea, vomiting, no pain......i was so thrilled. 5 days later after the prednisone wore off, I was AGAIN in hospital for SEVERE pain. Because no one knew that much about the procedure....they just tried to control the pain. Finally, a local oncologist told me that as these tumors begin to break up and disentiigrate it can be VERY painful.....and that during the prednisone treatment, this was masked. He gave me another 3 days of prednisone and pain medication to help through the rest of the week.
I have experienced great FATIGUE.....and continued (though milder) pain. This is the beginning of week 3 post Theraspheres.

I would not want anyone to be discouraged by my experience at all. I am certain that everyone's experience is different particularly given the huge range of past history etc. At the same time, I wish that someone had told ME of the possibilities.....that there can be intense pain. I am certain that an 8cm tumor must feel differently being treated than a smaller one.
I am now feeling much better.....am able to exercise and eat normally (after having no appetite). I have 2 more weeks before the 2nd
therasphere procedure. I am told that the right lobe of the liver is larger and more pain can be expected there. The left lobe, alternatively is smaller, and it is not likely there will be much pain.

I wish all of you great success and blessings with your treatments!!! I believe that theraspheres are an amazing miracle.....I call them the "magic orbs". I have heard from some people that tumors are completely destroyed and that liver transplantation is not necessary (depending on degree of liver disease, or course). In case no one has told you recently, You are BRAVE, COURAGEOUS, AND AMAZING to keep going....)

kohsin
Posts: 27
Joined: Apr 2010

Good luck Isabella. I have done Y-90 twice alone with embolization before the docs removed my 9 cm tumor. I had minimal side effect. other than fatigue, I was in great condition. So yes, Y-90 treatment is awesome and safe> I did mine here is UIC med and they have done this almost every week so it was a breeze for them. And by the way, This was back in 2009 and today's lab test showed all normal with AFP at 1.7. To all, do not give up, be strong and God Bless..

Mihali Dan
Posts: 2
Joined: Jun 2013

How much did you pay for two sessions of Y 90???Thank you!

Elizabeth55
Posts: 1
Joined: Sep 2011

this is great that all has gone good with the treatment..could you or anyone let me know if your tumor was in the center of your liver ...my partner has a 9cm tumor in the center of the liver..dr say he can not have transplant for its to large he is taking Nexavar 200mg per tab he taks 400mg morning and another 400mg at night and for his pain they put him on Fentanyl...this seems to work for a day or 2 then pain is back and just seems like more and more different pain hits..would like to know if anyone has had there tumor in center of the liver and recived help with it...I'm at a lose for what to do next:-(

thestarman
Posts: 1
Joined: Jun 2013

Hello Isabella, Thank you for your words of hope..My husband was just told he has HCC.  I have heard such good things about theresphere.  I am going to talk to the doctor about this.  I would like to know how you are doing now.  Thank you and god bless

Mihali Dan
Posts: 2
Joined: Jun 2013

How much Y 90 cost s?Thank you?

hepcat13
Posts: 2
Joined: Aug 2013

I had my first treatment with Therasphere 8/01/13 at Northwestern in Chicago. Follow-up MRI on 8/19 to dertermine shrinkage (not a Seinfeld reference). When billed, BCBS said the treatment MAY be experimental (it's not) and in that case my payment for the procedure would be $110,000. I assume this includes Interventional Radiology costs as well as anesthetic, X-ray room, etc. Yeah, it's REAL expensive, but it beats the alternative, which in my case is a permanent dirt nap. BE POSITIVE! Just keep swingin' Apollo!

 

 

 

 

RobM
Posts: 1
Joined: May 2013

Objectionable content removed by administrator.

XtremediverHCC
Posts: 60
Joined: Feb 2011

It appears you have nothing constructive or supportive to say or you would have noticed that others on here do indeed comment when they have an appropriate response.  In the time that I have been on it, this site has offered a wealth of knowledge, hope and encouragement that no other sites seem to offer.  It is support - by a community of human beings that know what it means to be affected by cancer; either directly or by a close relationship to an individual who is affected and that support is offered freely and without any restraint (other than not posting a response if you don't actually know what you are talking about).  My 6 year battle with cancer has been an up and down experience, but this site has always given me the support and strength to keep battling in the face of adversity. People like you should try to find something useful to spend their energy on rather than trying to post for the first time with such a stupid statement with no basis. If you have a legitimate question, please post it and if someone here can offer you an educated response they will, if not please just go away and stop making such an ass of yourself in public - your mom really wouldn't be too proud of you right now!

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