Cancer Survivors Network

Hello. My mom was diagnosed w/ a GBM and had surgery in October of 09. They were able to remove the whole tumor. She did the 6 weeks of radiation w/ 125 mg of Temodar and is currently finishing her 5th round of Temodar 250 mg, 5 day per month, 23 days off. She's been taking decadron off and on since the surgery, but more on than off. Her tumor was in her left frontal lobe, and this has made it difficult for her to communicate because she can't retrieve the words. These symptoms are directly related to brain swelling. Unfortunately, frontal lobe difficulties include far more than just speech. Its difficult for her to focus, concentrate, plan, sequence, prioritize and organize. Some times she seems like herself and others not so much, yet she's still in there. Her symptoms worsened and they did not respond to increasing the decadron and I was terrified the tumor grew back and I was right. Its very small and in the same place. They want to treat it w/ cyberknife, to shrink it and w/ Avastin and CPT-11. I'm wondering if anyone could share their experiences w/ Avasitn and CPT-11. My mom is 67 and her dream has always been to go to Italy. My sister and I are suppose to be taking her in July and we are praying she'll be up to going and be alert and aware enough to enjoy it. We were told that the cyberknife and the new chemo, if it works, will shrink the tumor and eventually decrease the swelling and that we should see some improvement again. Any experiences w/ these drugs would be appreciated. The list of possible side effects, as always, is frightening. Thank you so much :)