May 17, 2010 - 2:20 pm
After having a biopsy in February because my PSA had risn from 3.8 to 4.3 in 18 months the pathologist discovered 1 of 12 cores with adenocarcinoma with 15% involvement. DRE was normal and there were no physical symptoms. Gleason score was evaluated as 3+3=6. Staging was evaluated as T1c. A Bone scan, full blood panel, and chest x-ray indicated no evidence of PCa spread beyond the prostate. Prostate size was 47 cc which is relatively normal for a man my age (59).
I went through several weeks of consultations and research and ended up deciding to seek treatment using the Cyberknife method over surgery, proton treatment, or other forms of radiation. Although I was tempted to go the active surveillance route, I felt for someone my age with a 15+ year life expectancy that the more prudent course was to get treatment.
In preparing for the Cyberknife procedure I was required to get another PSA reading as the one that started the whole process was more than three months old. DRE in conjunction with pre-treatment was completely normal. Still have no other physical symptoms such as an enlarged prostaste, difficulty with urination, blood in urine, or erectile issues.
The most recent PSA was taken last week and came back at 2.8! I had expected a slight rise or something close to the earlier 4.3 reading but not such a significant decrease.
Since my diagnosis in March, I have eliminated dairy and red meat from my diet. One of my doctors treating me for elevated chloresterol also put me on a low dose of Crestor, a statin, in late January before I was diagnosed with PCa. Many of the studies I have read indicate that the elimination of dairy, the addition of soy, and statins have all been associated with reducing PSA levels but I was not prepared for such a dramatic drop.
While I will be consulting with the doctors this week on what this PSA decrease could mean, I was wondering if anyone else had experienced a significant PSA drop in early stage prostate cancer before treatment that could possibly be attributed to diet changes and the use of statins. There isn't much in the available literature that describes this type of PSA reduction except for some antecdotal case histories associated with the elimination of dairy products.
I realize, of course, that I still have PCa.
Any feedback would be appreciated.