Dec 10, 2009 - 6:06 pm
All this research recently posted plays into the research we did way way back into EGFR and how this factor GREATLY changes the prognosis of anyone with UPSC. And yet it is so hard to get the assays done! I pushed for it unsuccessfully after my initial diagnosis, but they just weren't doing that where I go. Now I see that I should have pushed harder or gone elsewhere, now that my cancer has recurred so quickly. I'll BET that I have most of those 'molecular factors' that would have predicted that my cancer would be resistant to chemo.
I'm not sure I wouldn't have fought for all of the pelvic radiation I received, so this may be a moot point, but I know now that pelvic radiation was a mistake in my case. For me it didn't prevent a recurrance in my pelvis, and now my bone marrow is really compromised from it. I may have a very hard time maintaining good enough RBC, WBC and plateletts to stay on the chemo I need to combat this recurrance, because my body is not yet recovered from my radiation.
BUT, had I known from the get-go that I had a VERY strong chance of recurring and almost no chance of a cure, I could have 'saved' my body for the expected recurrance. I could have taken treatment like the women with ovarian cancer do, (knowing their cancer will come back) taking a break from chemo when my CA-125 was normal and CT was clear and not pushing on with any further treatment until I started to show signs it was coming back again.
As sad as it would be to know almost from Day 1 that your cancer has a 90% chance of recurring (based on the tissue assays), you'd know not to go for 'overkill' in an attempt for a cure, and you'd have a stronger body to endure long-term cyclical repeated weaker chemo regimes.
Of course, I probably STILL would have wanted to slam my cancer with everything my body could bear. But maybe not. I think we have to encourage women with new UPSC diagnosis to get their fresh tissue analyzed for factors. That way they can make treatment decisions with open eyes.