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mesothelial cells in pelvic washings

geology's picture
geology
Posts: 12
Joined: Oct 2009

Hi I got a copy of my path report and pelvic washing report yesterday. The pelvic washing report said negative for malignancy but at end had a comment mesothelial cells noted. I have looked all over internet but can not figure out what it means. I do not have another appt for 3 weeks and have a hard time talking to Dr so any help would be appreciated. Also my path report said stage 1b grade 1 which is great with only superficial invasion into the myometrium, but I am confused by the actual diagnosis of endometriod adenocarcinoma with focal squamous metaplasia, endometrium. The focal squamous is where my confusion is, any thoughts would be appreciated. Thanks, Stephanie

california_artist
Posts: 850
Joined: Jan 2009

Stephnie
I plugged in the focal squamous metaplasia and endometrium

came up with this and some other things

http://www.ncbi.nlm.nih.gov/pubmed/7748076

Mentions progestin treatment

As for the mesothellial cells, there's this:

Department of Surgery, University of Western Australia, Royal Perth Hospital, Perth 6000, WA, Australia. mustaers@aari.uwa.edu.au

Mesothelial cells form a monolayer of specialised pavement-like cells that ___line the body's serous cavities and internal organs. The primary function of this layer, termed the mesothelium, is to provide a slippery, non-adhesive and protective surface. However, mesothelial cells play other pivotal roles involving transport of fluid and cells across the serosal cavities, antigen presentation, inflammation and tissue repair, coagulation and fibrinolysis and tumour cell adhesion. Injury to the mesothelium triggers events leading to the migration of mesothelial cells from the edge of the lesion towards the wound centre and desquamation of cells into the serosal fluid which attach and incorporate into the regenerating mesothelium. If healing is impaired, fibrous serosal adhesions form between organs and the body wall which impede vital intrathoracic and abdominal movement. Neoplastic transformation of mesothelial cells gives rise to malignant mesothelioma, an aggressive tumour predominantly of the pleura. Although closely associated with exposure to asbestos, recent studies have implicated other factors including simian virus 40 (SV40) in its pathogenesis.

Sounds as though they are just normally a lining.

Google is your friend. sometimes you have to keep on going to the bottom of the page and choosing NEXT, til you find what might apply to your situation. That linking hub thing will usually only give you an Abstract. I usually go til I find something from the NIH or a university, or a reputable hospital like M.D. Anderson or Mayo, Cleavland, etc...

Good hunting

geology's picture
geology
Posts: 12
Joined: Oct 2009

Thanks, It is so hard to sort through everything. I appreciate all the help I can get.

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